1. GPCR/G Protein
  2. Ras
  3. RAS GTPase inhibitor 1

RAS GTPase inhibitor 1 

Cat. No.: HY-129189
Handling Instructions

RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells.

For research use only. We do not sell to patients.

RAS GTPase inhibitor 1 Chemical Structure

RAS GTPase inhibitor 1 Chemical Structure

CAS No. : 2252242-32-1

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Description

RAS GTPase inhibitor 1 (example 51) is a RAS GTPase inhibitor with anti-tumor activity, extracted from patent WO2018212774A1. RAS GTPase inhibitor 1 (example 51) exhibits an EC50 less than 1 μM for at least one nucleotide exchange and an IC50 less than 1 μM in H727 cells[1].

IC50 & Target

IC50: < 1 μM (H727 cells)[1].
EC50: < 1 μM (nucleotide exchange)[1].

Molecular Weight

565.99

Formula

C₂₇H₂₈ClF₄N₅O₂

CAS No.

2252242-32-1

SMILES

CC[[email protected]@H](NC1=C2C=CC=C(C3=CCNCC3)C2=NC(NC4=CC=C(F)C(Cl)=C4)=N1)C5CC5.O=C(O)C(F)(F)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

RAS GTPase inhibitor 1RAS GTPase inhibitor1RAS GTPase inhibitor-1RasInhibitorinhibitorinhibit

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RAS GTPase inhibitor 1
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HY-129189
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