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Cat. No.: HY-123634

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(S)-3'-Aminoblebbistatin

(S)-3'-Aminoblebbistatin is the derivative of Blebbistatin (HY-13813). (S)-3'-Aminoblebbistatin exhibits inhibitory activity against myosin II with an IC₅₀ of 14.1 µM.

For research use only. We do not sell to patients.

CAS No.: 2097141-18-7
Formula: C₁₈H₁₇N₃O₂
Molecular Weight:307.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

(S)-3'-Aminoblebbistatin Chemical Structure

CAS No.: 2097141-18-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

(S)-3'-Aminoblebbistatin is the derivative of Blebbistatin (HY-13813). (S)-3'-Aminoblebbistatin exhibits inhibitory activity against myosin II with an IC₅₀ of 14.1 µM^[1].

All Myosin Isoforms :

MLCK

Chemical Information

CAS No. 2097141-18-7
Molecular Weight 307.35
Formula C₁₈H₁₇N₃O₂
SMILES

O[C@@]12C(N(C3=CC(N)=CC=C3)CC2)=NC4=CC=C(C)C=C4C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Verhasselt S, et al., Discovery of (S)-3'-hydroxyblebbistatin and (S)-3'-aminoblebbistatin: polar myosin II inhibitors with superior research tool properties. Org Biomol Chem. 2017 Mar 1;15(9):2104-2118. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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(S)-3'-Aminoblebbistatin

All Myosin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S)-3'-Aminoblebbistatin Related Classifications

HY-123634 Related Classifications