2. GPCR/G Protein Immunology/Inflammation
  3. CCR
  4. S-531011 (FUT8-KO)

S-531011 (FUT8-KO) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody. S-531011 (FUT8-KO) can be used for the research of cancer immunity.

For research use only. We do not sell to patients.

S-531011 (FUT8-KO)

S-531011 (FUT8-KO) Chemical Structure

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S-531011 (FUT8-KO) Related Antibodies

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

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Description

S-531011 (FUT8-KO) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody. S-531011 (FUT8-KO) can be used for the research of cancer immunity[1].

IC50 & Target[1]

CCR8

 

In Vitro

S-531011 (HY-P991481) is a human IgG1 monoclonal antibody (mAb) targeting CCR8. S-531011 reduces tumor-infiltrating CCR8+ Tregs and has anti-tumor activity in CT26.WT and EMT6 tumor-bearing mouse tumor models. S-531011 can be used in the study of cancer immunity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

S-531011 (FUT8-KO) Related Antibodies
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S-531011 (FUT8-KO) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-531011 (FUT8-KO)CCRCC chemokine receptorInhibitorinhibitorinhibit

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