1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-C4-NH2 dihydrochloride

(S,R,S)-AHPC-C4-NH2 dihydrochloride (Synonyms: VH032-C4-NH2 dihydrochloride)

Cat. No.: HY-114176B
Handling Instructions

(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC.

For research use only. We do not sell to patients.

(S,R,S)-AHPC-C4-NH2 dihydrochloride Chemical Structure

(S,R,S)-AHPC-C4-NH2 dihydrochloride Chemical Structure

CAS No. : 2341796-78-7

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Description

(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

IC50 & Target

VHL

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

602.62

Formula

C₂₇H₄₁Cl₂N₅O₄S

CAS No.

2341796-78-7

SMILES

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[[email protected]]3N(C([[email protected]](C(C)(C)C)NC(CCCCN)=O)=O)C[[email protected]](O)C3.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(S,R,S)-AHPC-C4-NH2VH032-C4-NH2E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Product name:
(S,R,S)-AHPC-C4-NH2 dihydrochloride
Cat. No.:
HY-114176B
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