1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. E3 ligase Ligand-Linker Conjugates 28

E3 ligase Ligand-Linker Conjugates 28 

Cat. No.: HY-114176 Purity: 95.26%
Handling Instructions

E3 ligase Ligand-Linker Conjugates 28 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

For research use only. We do not sell to patients.

E3 ligase Ligand-Linker Conjugates 28 Chemical Structure

E3 ligase Ligand-Linker Conjugates 28 Chemical Structure

CAS No. : 2245697-83-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 605 In-stock
Estimated Time of Arrival: December 31
100 mg USD 550 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
1 g USD 3350 In-stock
Estimated Time of Arrival: December 31
2 g USD 4900 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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  • Technical Information

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Description

E3 ligase Ligand-Linker Conjugates 28 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

IC50 & Target[1]

VHL

 

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 109.6 mg/mL (193.58 mM)

H2O : ≥ 50 mg/mL (88.31 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7663 mL 8.8314 mL 17.6629 mL
5 mM 0.3533 mL 1.7663 mL 3.5326 mL
10 mM 0.1766 mL 0.8831 mL 1.7663 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

566.16

Formula

C₂₇H₄₀ClN₅O₄S

CAS No.

2245697-83-8

SMILES

O=C(N[[email protected]@H](C(C)(C)C)C(N1C[[email protected]](O)C[[email protected]]1C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)=O)CCCCN.[H]Cl

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Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
E3 ligase Ligand-Linker Conjugates 28
Cat. No.:
HY-114176
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E3 ligase Ligand-Linker Conjugates 28

Cat. No.: HY-114176