(S,R,S)-AHPC(Me)-amido-C2-acid
Based on 1 Customer Validation
(S,R,S)-AHPC(Me)-amido-C2-acid is an VHL (E3 ligase) ligand, and can be used for synthesis of PROTACs, such as PROTAC STING Degrader-2 (HY-158036).
For research use only. We do not sell to patients.
- Purity : 95.05%
- CAS No.: 2365173-01-7
- Formula: C27H36N4O6S
- Molecular Weight:544.66
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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VHL |
Chemical Information
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CAS No. 2365173-01-7
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Appearance Solid
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Molecular Weight 544.66
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Formula C27H36N4O6S
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Color White to off-white
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SMILES
OC(CCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (45.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.8360 mL | 9.1800 mL | 18.3601 mL | 45.9002 mL |
| 5 mM | 0.3672 mL | 1.8360 mL | 3.6720 mL | 9.1800 mL | |
| 10 mM | 0.1836 mL | 0.9180 mL | 1.8360 mL | 4.5900 mL | |
| 15 mM | 0.1224 mL | 0.6120 mL | 1.2240 mL | 3.0600 mL | |
| 20 mM | 0.0918 mL | 0.4590 mL | 0.9180 mL | 2.2950 mL | |
| 25 mM | 0.0734 mL | 0.3672 mL | 0.7344 mL | 1.8360 mL | |
| 30 mM | 0.0612 mL | 0.3060 mL | 0.6120 mL | 1.5300 mL | |
| 40 mM | 0.0459 mL | 0.2295 mL | 0.4590 mL | 1.1475 mL |
(S,R,S)-AHPC(Me)-amido-C2-acid Related Classifications
HY-164043 Related Classifications
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