2365173-01-7
2365173-01-7
Chemical Structure
(S,R,S)-AHPC-Me-CO-C2-COOH
- CAS No.: 2365173-01-7
- Formula:C27H36N4O6S
- Molecular Weight:544.67
IUPAC Name: 4-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
InChIKey: NMPQIUBZJDYREV-RXYORGTDSA-N
SMILES: C([C@@H](NC(CCC(O)=O)=O)C(C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
Biological Activity: (S,R,S)-AHPC-Me-CO-C2-COOH is an E3 ligase ligand-linker conjugate containing a VHL ligand and linker based on (S,R,S)-AHPC. (S,R,S)-AHPC-Me-CO-C2-COOH can be used to synthesize PROTAC.
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(S,R,S)-AHPC-Me-CO-C2-COOH | (S,R,S)-AHPC-Me-CO-C2-COOH is an E3 ligase ligand-linker conjugate containing a VHL ligand and linker based on (S,R,S)-AHPC. (S,R,S)-AHPC-Me-CO-C2-COOH can be used to synthesize PROTAC. | |||||||||||||||||||||
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(S,R,S)-AHPC(Me)-amido-C2-acid | 95.05% | (S,R,S)-AHPC(Me)-amido-C2-acid is an VHL (E3 ligase) ligand, and can be used for synthesis of PROTACs, such as PROTAC STING Degrader-2 (HY-158036). | ||||||||||||||||||||
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