2. Natural Products
  3. Plants Saccharides
  4. Schisandraceae Monosaccharides
  5. Schisandra chinensis (Turcz.) Baill.
  6. Schisandrastemoside A

Schisandrastemoside A (Compound 3) is a lignan found in the rattan stems of Schisandra chinensis. Schisandrastemoside A shows neuroprotective efect and protects cells against Amyloid-beta 1-42 (HY-P1363A)-induced neurotoxicity. Schisandrastemoside A can be used for the research of Alzheimer's disease.

For research use only. We do not sell to patients.

Schisandrastemoside A

Schisandrastemoside A Chemical Structure

CAS No. : 2014382-50-2

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Schisandrastemoside A Related Antibodies

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Description

Schisandrastemoside A (Compound 3) is a lignan found in the rattan stems of Schisandra chinensis. Schisandrastemoside A shows neuroprotective efect and protects cells against Amyloid-beta 1-42 (HY-P1363A)-induced neurotoxicity. Schisandrastemoside A can be used for the research of Alzheimer's disease[1].

In Vitro

Schisandrastemoside A (5-25 μM; 24 h) potently protects PC12 cells from Amyloid-beta 1-42 (HY-P1363A)-induced toxicity in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Schisandrastemoside A Related Antibodies

Cell Viability Assay[1]

Cell Line: PC12 cells
Concentration: 5, 12.5, 25 μM
Incubation Time: 24 h ( with amyloid-beta 1-42 exposure)
Result: Increased cell viability to 54.7 ± 3.4% at 5 μM.
Increased cell viability to 62.8 ± 3.8% at 12.5 μM.
Increased cell viability to 82.1 ± 4.3% at 25 μM.
Produced statistically significant increases in cell viability relative to the amyloid-beta 1-42-only model group at 12.5 μM and 25 μM.
Molecular Weight

566.59

Formula

C28H38O12
CAS No.
SMILES

O[C@@]1(C)[C@H](C)CC2=CC(O)=C(OC)C(OC)=C2C3=C(C=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C(OC)=C3OC)C1
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Schisandrastemoside A Related Classifications

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Keywords:

Schisandrastemoside A2014382-50-2Othersneurotoxicityneuroprotectivealzheimer's diseasePC12Schisandra chinensisamyloid-beta 1-42Inhibitorinhibitorinhibit

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