BSF-466895
BSF-466895(A-422885.66) is a Tie2 inhibitor with an IC50 of 5 nM and it can also inhibit Tie1.
For research use only. We do not sell to patients.
- CAS No.: 262442-90-0
- Formula: C29H32Cl2FN7O2S
- Molecular Weight:632.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Tie2 5 nM (IC50) |
Chemical Information
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CAS No. 262442-90-0
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Molecular Weight 632.58
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Formula C29H32Cl2FN7O2S
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SMILES
O=S(C1=CC=CC(Cl)=C1Cl)(NC2=CC=C(C3=CN([C@H]4CC[C@H](N5CCN(C)CC5)CC4)C6=NC=NC(N)=C63)C=C2F)=O
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Synonyms
A-422885.66
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jerry Adams, et al. A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis. Curr Opin Chem Biol. 2002 Aug;6(4):486-92. [Content Brief]
[2]. Dieter Marmé, et al. The impact of anti-angiogenic agents on cancer therapy. J Cancer Res Clin Oncol. 2003 Nov;129(11):607-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)