315 Results for "

Biocompatibility

" in MedChemExpress (MCE) Product Catalog:
Products (315)

315 Results for "Biocompatibility" in MCE Product Catalog:

Cat. No.: HY-158222
Synonyms: AlgMA (MW 50000)
Alginate Methacryloyl (MW 50000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 50000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 50000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.
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Cat. No.: HY-158222A
Synonyms: AlgMA (MW 300000)
Research Areas:  

Others

Alginate Methacryloyl (MW 300000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 300000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 300000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.
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Cat. No.: HY-B2221C
CAS No.: 9000-11-7
Synonyms: Carboxymethyl cellulose CM-32; CM-32
CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research .
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Cat. No.: HY-180825
Anticancer agent 292 (Compound P4) is a photosensitizer for anti-melanoma. Anticancer agent 292 shows good biocompatibility under dark conditions and, upon illumination, induces apoptosis and partial necrosis in B16-F10 cells by disrupting the lysosomal membrane. Anticancer agent 292 not only directly kills tumor cells through the generation of reactive oxygen species (ROS), but also induces immune-prone cell death (ICD), thereby generating anti-tumor immune effects. Anticancer agent 292 can be used in the research of photodynamic therapy for melanoma .
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Cat. No.: HY-184618
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. Surface modification of palladium nanoparticles with sodium citrate can significantly improve their dispersibility, stability, and biocompatibility, and facilitate further coupling with other biomolecules or fluorescent molecules.
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Cat. No.: HY-184619
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. PEI surface modification of palladium nanoparticles can significantly improve their dispersibility, stability, and biocompatibility, and facilitate further coupling with other biomolecules or fluorescent molecules.
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Cat. No.: HY-184638
APTS Fe2O3 Nanoparticles (Aminated ferric oxide magnetic nanoparticles) are magnetic nanomaterials modified with amino functional groups using APTS. This material consists of a ferric oxide (Fe3O4) nanoparticle core and an amino (-NH2) surface modification layer. The aminated surface helps improve the biocompatibility of the nanoparticles and reduce cytotoxicity. The amino functional groups can be further chemically modified for coupling with biomolecules such as drugs, proteins, and nucleic acids. The amino functional groups undergo protonation at different pH values, resulting in different surface charges on the nanoparticles in different pH environments.
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Cat. No.: HY-B0633C
CAS No.: 9004-61-9
Hyaluronic acid (Mw: 1000-2000 Da) is a long-chain unbranched polysaccharide with a molecular weight of 1000-2000 Da. Hyaluronic acid (Mw: 2000 Da) inhibits IL-1β expression and increases LC3-II. Hyaluronic acid (Mw: 1000-2000Da) can regulate tissue homeostasis and stress resistance, promote angiogenesis and tissue remodeling. Hyaluronic acid (Mw: 1000-2000 Da) has good biocompatibility and biodegradability, and can be used in drug delivery systems and tissue engineering. Hyaluronic acid (Mw: 2000 Da) can reduce facial skin blemishes and sagging .
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Cat. No.: HY-W888515
Research Areas:  

Neurological Disease

mPEG-PCL is an amphiphilic biodegradable block copolymer composed of hydrophilic methoxy poly (ethylene glycol) (mPEG) and hydrophobic poly (ε-caprolactone) (PCL). mPEG-PCL possesses excellent biocompatibility and can form delivery carriers such as micelles and nanoparticles. Through its amphiphilic block structure, mPEG-PCL forms nanocarriers and encapsulates hydrophobic molecules, thereby enhancing the loading capacity of hydrophobic molecules, reducing burst release, and achieving sustained release. mPEG-PCL can be used in research on nanodelivery, tissue engineering, and ocular delivery systems related to age-related macular degeneration (AMD) .
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Cat. No.: HY-158220
Synonyms: HAMA (MW 400 kDa)
Hyaluronic acid Methacryloyl (MW 400 kDa) (HAMA (MW 400 kDa)) is a methacrylated hyaluronic acid with biocompatibility. Hyaluronic acid Methacryloyl (MW 400 kDa) also serves as a 3D printing hydrogel ink, featuring rapid photoresponsiveness, fast gelation speed and stable hydrogel performance. Hyaluronic acid Methacryloyl (MW 400 kDa) can rapidly initiate gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) under ultraviolet irradiation. Moreover, the combination of Hyaluronic acid Methacryloyl with tissue-specific extracellular matrix (ECM) materials (such as pancreatic extracellular matrix (pECM)) acts as an important source material for organoid culture .
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Cat. No.: HY-D3099
CAS No.: 3078752-74-3
Target:  

Fluorescent Dye

Research Areas:  

Others

CSMPP is a ratiometric lysosomal pH fluorescent probe with aggregation-induced emission (AIE) properties, which is used for real-time quantitative detection of lysosomal pH changes in living cells and in vivo. CSMPP has a cyanodistyrene backbone, and contains N-methylpiperazine and pyridine groups (pH-responsive); protonation of the pyridine group significantly enhances intramolecular charge transfer (ICT), leading to green fluorescence emission (Ex/Em = 405/503 nm) under neutral/basic conditions and red fluorescence emission (Ex/Em = 405/615 nm) under acidic conditions. CSMPP exhibits high selectivity, reversibility, good biocompatibility and excellent photostability .
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Cat. No.: HY-D3164
CAS No.: 1380316-56-2
Target:  

Fluorescent Dye

Research Areas:  

Others

TPE-Cy is a fluorescent probe with both aggregation-induced emission (AIE) property and pH-dependent luminescent behavior. TPE-Cy exhibits significant luminescent differences under different acidic and alkaline conditions: it shows moderate to strong red emission with linear variation with pH in acidic environments and within the pH range of 5-7, weak or even no emission within the pH range of 7-10, and switches to blue emission under alkaline conditions. TPE-Cy possesses excellent cell permeability and biocompatibility, enabling accurate ratiometric pH sensing and imaging monitoring in living cells via confocal microscopy, ratiometric analysis and flow cytometry .
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Cat. No.: HY-W584165
CAS No.: 13983-17-0
Wollastonite is a white, chain-structured pyroxene silicate mineral with biocompatibility, biodegradability, osteogenicity and antibacterial properties. Wollastonite induces transient pulmonary inflammatory responses, reversible alveolar macrophage responses, early inflammatory/proliferative mesothelial cell responses, ROS production, and mild chronic pulmonary interstitial inflammation in rats. Wollastonite induces osteogenic differentiation, promotes bone growth, supports angiogenesis, and facilitates the formation of hydroxycarbonate apatite on its surface. Wollastonite enhances the strength, bioactivity and biodegradability of hydroxyapatite scaffolds, and is used to construct porous bone tissue engineering scaffolds. Wollastonite is applied in research related to diseases such as bronchitis, decreased lung function and bone defects .
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Cat. No.: HY-112624K
CAS No.: 9004-54-0
Synonyms: Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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Cat. No.: HY-184611
Selenium (Se) is an essential trace element for the human body, playing a vital role in various physiological activities. In the body, selenium is bound to selenocysteine, an amino acid used to synthesize several selenoproteins. Selenium is often the active site of these proteins, playing a crucial role in maintaining intracellular redox balance. Chitosan-stabilized selenium nanoparticles (CS-SeNPs) are nanomaterials using the biopolymer chitosan (CS) as a stabilizer. Through electrostatic interactions, chitosan coats the surface of selenium nanoparticles (Se NPs), improving their dispersibility, stability, and biocompatibility. Se NPs themselves are characterized by low toxicity and high bioactivity, and the introduction of chitosan further enhances their functionality and application potential, making them widely recognized in biomedicine, food, and agriculture.
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Cat. No.: HY-W008034S
CAS No.: 1325307-52-5
Synonyms: Fmoc-L-Trp(Boc)-OH-13C11,15N2
Fmoc-Trp(Boc)-OH- 13C11, 15N2 (Fmoc-L-Trp(Boc)-OH- 13C11, 15N2) is the 13C-labeled and 15N-labeled Fmoc-Trp(Boc)-OH (HY-W008034). Fmoc-Trp(Boc)-OH (Fmoc-L-Trp(Boc)-OH) is an amino acid derivative with protective groups. Fmoc-Trp(Boc)-OH can self-assemble into stable and pH-responsive spherical nanoparticles, which can load and release bioactive molecules, with good biocompatibility and high cell uptake rate. Fmoc-Trp(Boc)-OH can be used in research on drug delivery .
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Cat. No.: HY-W250121
CAS No.: 9000-65-1
Tragacanth gum is an orally active anionic composite polysaccharide and multifunctional biomaterial. Tragacanth gum exhibits biocompatibility, mucoadhesion and renoprotective effects, and effectively promotes wound closure and tissue healing. Tragacanth gum can be isolated from Astragalus gummifer. Tragacanth gum acts as an emulsifier and drug delivery carrier, and is also widely used in fields such as 3D scaffolds, tissue engineering and green nanoparticle preparation. High doses of Tragacanth gum may induce reversible forestomach squamous epithelial hyperplasia in mice, but show no mutagenic or carcinogenic activity. Tragacanth gum is commonly used in studies related to diseases including systemic candidiasis, rheumatoid arthritis and osteosarcoma .
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Cat. No.: HY-L255
72 compounds

Dipeptide compounds have attracted extensive attention in drug discovery and life science research due to their simple structures, ease of modification, and favorable biocompatibility. As small peptides composed of two amino acids, dipeptides exhibit diverse biological activities, including anti-inflammatory, antioxidant, antimicrobial, anticancer, and immunomodulatory effects, showing significant application potential in metabolic disorders, neurological diseases, and cancer research. Compared with traditional small molecules, dipeptide compounds possess favorable target-binding properties and high structural plasticity, making them valuable tools for drug screening and mechanism studies.

The MCE Dipeptide Compound Library contains 72 dipeptide compounds and can be applied to peptide drug discovery and development.

Cat. No.: HY-112624O
CAS No.: 9004-54-0
Synonyms: Dextran 100; Dextran D100; Dextran T100(MW 90000-110000)
Dextran T100 (MW 100,000) (Dextran 100; Dextran D100) is a dehydrated glucose polymer with an average molecular weight of 100,000. Dextran T100 (MW 100,000) has an α-(1→6)-linked D-glucose backbone and α-(1→4)-, α-(1→3)- or α-(1→2)-linked D-glucose side chains, and it is synthesized by lactic acid bacteria or their enzymes. Dextran T100 (MW 100,000) possesses favorable biodegradability and biocompatibility, and it can be used in the fields of food, pharmaceuticals, cosmetics and research .
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Cat. No.: HY-116282W
CAS No.: 9011-18-1
Synonyms: DSS (MW 6500-10000); DXS (MW 6500-10000)
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .
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