9000-65-1
Chemical Structure
Biological Activity: Tragacanth gum is an orally active anionic composite polysaccharide and multifunctional biomaterial. Tragacanth gum exhibits biocompatibility, mucoadhesion and renoprotective effects, and effectively promotes wound closure and tissue healing. Tragacanth gum can be isolated from Astragalus gummifer. Tragacanth gum acts as an emulsifier and drug delivery carrier, and is also widely used in fields such as 3D scaffolds, tissue engineering and green nanoparticle preparation. High doses of Tragacanth gum may induce reversible forestomach squamous epithelial hyperplasia in mice, but show no mutagenic or carcinogenic activity. Tragacanth gum is commonly used in studies related to diseases including systemic candidiasis, rheumatoid arthritis and osteosarcoma[1][2][3].
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Tragacanth gum | Tragacanth gum is an orally active anionic composite polysaccharide and multifunctional biomaterial. Tragacanth gum exhibits biocompatibility, mucoadhesion and renoprotective effects, and effectively promotes wound closure and tissue healing. Tragacanth gum can be isolated from Astragalus gummifer. Tragacanth gum acts as an emulsifier and drug delivery carrier, and is also widely used in fields such as 3D scaffolds, tissue engineering and green nanoparticle preparation. High doses of Tragacanth gum may induce reversible forestomach squamous epithelial hyperplasia in mice, but show no mutagenic or carcinogenic activity. Tragacanth gum is commonly used in studies related to diseases including systemic candidiasis, rheumatoid arthritis and osteosarcoma. | |||||||||||||||||||||
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- [1]. Nazemi Z, et al. A review on tragacanth gum: A promising natural polysaccharide in drug delivery and cell therapy. Int J Biol Macromol. 2023;241:124343. [Content Brief]
- [2]. Taghavizadeh Yazdi ME, et al. Gum Tragacanth (GT): A Versatile Biocompatible Material beyond Borders. Molecules. 2021;26(6):1510. Published 2021 Mar 10. [Content Brief]
- [3]. Hagiwara A, et al. Oral toxicity study of tragacanth gum in B6C3F1 mice: development of squamous-cell hyperplasia in the forestomach and its reversibility. J Toxicol Environ Health. 1991;34(2):207-218. [Content Brief]
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