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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
351 Results for "
Sarcoma
" in MedChemExpress (MCE) Product Catalog:
Products (351)
351 Results for "Sarcoma" in MCE Product Catalog:
Cat. No.: HY-119143
CAS No.: 32093-09-7
Research Areas:
CB 3703 is an inhibitor of thymidylate synthase (TS) and dihydrofolate reductase (DHFR). CB 3703 has an IC50 of 0.25 μM against rat TS, a Ki of 0.47 μM against mouse TS, an IC50 of 6.8 nM against rat DHFR, and a Ki of 0.6 pM against mouse DHFR. CB 3703 is transported via the reduced folate pathway, has a short plasma half-life, and can prolong the survival of tumor-bearing mice. CB 3703 can be used in the research of L1210 ascites tumors .
Target:
Research Areas:
dTAGV-1-NEG is an inactive FKBP12 F36V PROTAC degrader, the diastereomer of dTAGV-1 (HY-145514D), and a heterobifunctional negative control molecule. dTAGV-1-NEG does not degrade any protein .
Cat. No.: HY-145514B
Target:
Research Areas:
dTAGV-1-NEG TFA is an inactive FKBP12 F36V PROTAC degrader, the diastereomer of dTAGV-1 (HY-145514D), and a heterobifunctional negative control molecule. dTAGV-1-NEG TFA does not degrade any protein .
Cat. No.: HY-W001951
CAS No.: 15956-28-2
Synonyms: Tetrakis(acetato)dirhodium(II); Rhodium(II) acetate dimer
Cat. No.: HY-P75921
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K8; Proto-Oncogene Serine/Threoine Protein Kinase; Prev. ESTF; Cot (Cancer Osaka Thyroid) Oncogene; Prev. COT; Serine/Threonine-Protein Kinase Cot; Tumor Progression Locus 2; Cancer Osaka Thyroid Oncogene; Tpl-2; Ewing Sarcoma Transformant; C-COT; AUR
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P76294
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P76295
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1R; CSF-1R; Prev. FMS; Macrophage Colony Stimulating Factor I Receptor; C-FMS; Colony Stimulating Factor Receptor; CD115; Receptor Protein-Tyrosine Kinase; CSFR; FMS Proto-Oncogene; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; BANDDOS; Macr
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P702691
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: KIT; C-Kit Protooncogene; Prev. PBT; Platelet-Derived Growth Factor Receptor-Like Protein; Mast/Stem Cell Growth Factor Receptor Kit; Mast/Stem Cell Growth Factor Receptor Variant; SCFR; Proto-Oncogene Tyrosine-Protein Kinase Kit; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Mast/Stem Cell Growth Factor Receptor; Tyrosine-Protein Kinase Kit; Receptor Protein-Tyrosine Kinase; Proto-Oncogene C-Kit; Alternative Protein KIT; C-Kit; Piebald Trait; CD117; CD117 Antigen; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein; KIT Protein; Piebald Trait Protein; MASTC; KIT Proto-Oncogene, Receptor Tyrosine Kinase; P145 C-Kit
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705187
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KIT; C-Kit Protooncogene; Prev. PBT; Platelet-Derived Growth Factor Receptor-Like Protein; Mast/Stem Cell Growth Factor Receptor Kit; Mast/Stem Cell Growth Factor Receptor Variant; SCFR; Proto-Oncogene Tyrosine-Protein Kinase Kit; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Mast/Stem Cell Growth Factor Receptor; Tyrosine-Protein Kinase Kit; Receptor Protein-Tyrosine Kinase; Proto-Oncogene C-Kit; Alternative Protein KIT; C-Kit; Piebald Trait; CD117; CD117 Antigen; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein; KIT Protein; Piebald Trait Protein; MASTC; KIT Proto-Oncogene, Receptor Tyrosine Kinase; P145 C-Kit
Species:
Cynomolgus
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-159803
CAS No.: 128201-92-3
Synonyms: 6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin
Target:
Research Areas:
IST-622 (6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin) is an anti-tumor agent with significant growth inhibitory activity. IST-622 exhibits significant anti-tumor effects against a variety of mouse tumors such as P388 and L1210 leukemias, B16 melanoma, Lewis lung carcinoma, Colon 26 and Colon 38 adenocarcinomas, and M5076 reticulum cell sarcoma. IST-622 was orally administered and the results showed efficacy in different tumor types. In addition, IST-622 provided significant inhibitory effects against two human tumor xenograft models: large cell lung carcinoma (Lu-116) and gastric adenocarcinoma (St-4). IST-622 also exhibited significant growth inhibitory activity against P388 leukemia in vitro, with a half inhibitory concentration (IC50) more than 20 times lower than CT .
Cat. No.: HY-173273
CAS No.: 3031861-18-1
Target:
Research Areas:
YJZ5118 is a selective CDK12/CDK13 inhibitor with IC50 values of 39.5 nM and 26.4 nM. YJZ5118 suppresses transcription of DNA damage response genes and induces DNA damage in tumor cells. YJZ5118 inhibits proliferation and triggers apoptosis. YJZ5118 inhibits RNA polymerase II Ser2 phosphorylation and increases Akt pathway activity. YJZ5118 exhibits synergistic effects with Akt inhibitors. YJZ5118 can be used for the research of cancer, such as prostate cancer .
Cat. No.: HY-178861
Target:
Research Areas:
dCDK9-202 is a CDK9 PROTAC degrader with a DC50 of 3.5 nM. dCDK9-202 induces CDK9 degradation via the ubiquitin-proteasome system. dCDK9-202 inhibits the growth of cancer cells in vitro and suppresses tumor growth in mouse xenograft models. dCDK9-202 is applicable for cancer-related research .
Cat. No.: HY-P701957
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PATZ1; POZ-, AT Hook-, And Zinc Finger-Containing Protein 1; Prev. ZNF278; Zinc Finger And BTB Domain-Containing Protein 19; ZBTB19; Zinc Finger Sarcoma Gene Protein; RIAZ; BTB-POZ Domain Zinc Finger Transcription Factor; PATZ; BTB/POZ Domain Zinc Finger
Species:
E.coli
Source:
E. coli
Cat. No.: HY-P810292
Synonyms: Bromodomain containing 9 antibody;
Bromodomain containing protein 9 antibody;
DKFZp434D0711 antibody;
DKFZp686L0539 antibody;
FLJ13441 antibody;
LAVS3040 antibody;
PRO9856 antibody;
RhabdomyoSarcoma antigen MU RMS 40.8 antibody;
Sarcoma antigen NY SAR 29 antibody;
UNQ3040 antibody
Cat. No.: HY-P702714
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ROS1; Proto-Oncogene C-Ros-1; ROS Proto-Oncogene 1, Receptor Tyrosine Kinase; V-Ros UR2 Sarcoma Virus Oncogene Homolog 1 (Avian); MCF3; ROS Proto-Oncogene 1 , Receptor Tyrosine Kinase; ROS; Transmembrane Tyrosine-Specific Protein Kinase; C-Ros-1; Receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702725
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: YES1; YES Proto-Oncogene 1; Src Family Tyrosine Kinase; HsT441; C-Yes; Yes; V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1; Tyrosine-Protein Kinase Yes; Proto-Oncogene C-Yes; YES1 Proto-Oncogene; Src Family Tyrosine Kinase; Proto-Oncogene Tyrosine-Protein Ki
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706024
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KIT; C-Kit Protooncogene; Prev. PBT; Platelet-Derived Growth Factor Receptor-Like Protein; Mast/Stem Cell Growth Factor Receptor Kit; Mast/Stem Cell Growth Factor Receptor Variant; SCFR; Proto-Oncogene Tyrosine-Protein Kinase Kit; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Mast/Stem Cell Growth Factor Receptor; Tyrosine-Protein Kinase Kit; Receptor Protein-Tyrosine Kinase; Proto-Oncogene C-Kit; Alternative Protein KIT; C-Kit; Piebald Trait; CD117; CD117 Antigen; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein; KIT Protein; Piebald Trait Protein; MASTC; KIT Proto-Oncogene, Receptor Tyrosine Kinase; P145 C-Kit
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706025
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KIT; C-Kit Protooncogene; Prev. PBT; Platelet-Derived Growth Factor Receptor-Like Protein; Mast/Stem Cell Growth Factor Receptor Kit; Mast/Stem Cell Growth Factor Receptor Variant; SCFR; Proto-Oncogene Tyrosine-Protein Kinase Kit; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Mast/Stem Cell Growth Factor Receptor; Tyrosine-Protein Kinase Kit; Receptor Protein-Tyrosine Kinase; Proto-Oncogene C-Kit; Alternative Protein KIT; C-Kit; Piebald Trait; CD117; CD117 Antigen; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein; KIT Protein; Piebald Trait Protein; MASTC; KIT Proto-Oncogene, Receptor Tyrosine Kinase; P145 C-Kit
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706026
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KIT; C-Kit Protooncogene; Prev. PBT; Platelet-Derived Growth Factor Receptor-Like Protein; Mast/Stem Cell Growth Factor Receptor Kit; Mast/Stem Cell Growth Factor Receptor Variant; SCFR; Proto-Oncogene Tyrosine-Protein Kinase Kit; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Mast/Stem Cell Growth Factor Receptor; Tyrosine-Protein Kinase Kit; Receptor Protein-Tyrosine Kinase; Proto-Oncogene C-Kit; Alternative Protein KIT; C-Kit; Piebald Trait; CD117; CD117 Antigen; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein; KIT Protein; Piebald Trait Protein; MASTC; KIT Proto-Oncogene, Receptor Tyrosine Kinase; P145 C-Kit
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706027
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KIT; C-Kit Protooncogene; Prev. PBT; Platelet-Derived Growth Factor Receptor-Like Protein; Mast/Stem Cell Growth Factor Receptor Kit; Mast/Stem Cell Growth Factor Receptor Variant; SCFR; Proto-Oncogene Tyrosine-Protein Kinase Kit; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Mast/Stem Cell Growth Factor Receptor; Tyrosine-Protein Kinase Kit; Receptor Protein-Tyrosine Kinase; Proto-Oncogene C-Kit; Alternative Protein KIT; C-Kit; Piebald Trait; CD117; CD117 Antigen; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein; KIT Protein; Piebald Trait Protein; MASTC; KIT Proto-Oncogene, Receptor Tyrosine Kinase; P145 C-Kit
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
