348 Results for "

obstructive

" in MedChemExpress (MCE) Product Catalog:
Products (348)

348 Results for "obstructive" in MCE Product Catalog:

Cat. No.: HY-176512
CAS No.: 3100308-37-7
Target:  

Liposome

Research Areas:  

Others

FO-32 is an ionizable lipid and mRNA delivery carrier with state-of-the-art aerosolized mRNA delivery capability. FO-32 delivers mRNA to mouse muscle, nasal mucosa, lung, as well as ferret lung epithelium (including conducting airways). FO-32 can be used in studies related to the generation of lipid nanoparticles (LNPs) and the optimization of drug delivery .
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Cat. No.: HY-184098
CAS No.: 2770252-94-1
Synonyms: Lomasemtivum
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Lomasemtiv (Lomasemtivum) is a Troponin activator. Lomasemtiv activates skeletal muscle myofibrils. Lomasemtiv is applicable to sarcopenia research .
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Cat. No.: HY-184076
CAS No.: 2978107-47-8
Research Areas:  

Inflammation/Immunology Cancer

Ibrilparant is a LPA1 receptor antagonist with an IC50 of 0.00753 μM. Ibrilparant exhibits LPA1 calcium flux antagonistic activity, with an IC50 of 3.02 nM. Ibrilparant can be used in research related to various diseases such as cancer and inflammatory diseases .
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Cat. No.: HY-N2593R
CAS No.: 32507-66-7
Isorhapontigenin (Standard) is the analytical standard of Isorhapontigenin (HY-N2593). This product is intended for research and analytical applications. Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes.
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Cat. No.: HY-186050
CAS No.: 3105300-99-7
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

GIPR antagonist 2 is a glucose-dependent insulinotropic polypeptide receptor (GIPR) antagonist with an IC50 of 7.2 nM in CHO-K1 cells. GIPR antagonist 2 can be used in research related to diseases such as obesity, type 2 diabetes, non-alcoholic fatty liver disease, and atherosclerosis .
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Cat. No.: HY-B0267B
CAS No.: 1207344-05-5
Synonyms: Aroxybutynin hydrochloride
Target:  

mAChR

Research Areas:  

Neurological Disease

(R)-Oxybutynin hydrochloride (Aroxybutynin hydrochloride), an enantiomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride exhibits antispasmodic and anticholinergic activities, and competitively antagonizes carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used in the research of urinary incontinence caused by neurogenic bladder dysfunction .
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Cat. No.: HY-B0267BS
Research Areas:  

Neurological Disease

Oxybutynin-d5 hydrochloride is the d5-labeled (R)-Oxybutynin hydrochloride (HY-B0267B). (R)-Oxybutynin hydrochloride (Aroxybutynin hydrochloride), an enantiomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride exhibits antispasmodic and anticholinergic activities, and competitively antagonizes carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used in the research of urinary incontinence caused by neurogenic bladder dysfunction .
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Cat. No.: HY-B0267C
CAS No.: 119618-21-2
Synonyms: Aroxybutynin
Target:  

mAChR

Research Areas:  

Neurological Disease

(R)-Oxybutynin (Aroxybutynin), an enantiomer of Oxybutynin, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin exhibits antispasmodic and anticholinergic activities, and competitively antagonizes carbachol-induced contractions. (R)-Oxybutynin can be used in the research of urinary incontinence caused by neurogenic bladder dysfunction .
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