Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
ASA
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "ASA" in MCE Product Catalog:
Research Areas:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
Aspirin (Acetylsalicylic Acid) lithium is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin lithium induces apoptosis. Aspirin lithium inhibits the activation of NF-κB. Aspirin lithium also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis .
Cat. No.: HY-W206016S
Synonyms: 3-ASA-d3
Cat. No.: HY-RS18745
Target:
Research Areas:
Arsa Mouse Pre-designed siRNA Set A contains three designed siRNAs for Arsa gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01034
Target:
Research Areas:
ARSA Human Pre-designed siRNA Set A contains three designed siRNAs for ARSA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-B0174AR
CAS No.: 15722-48-2
Target:
Research Areas:
Olsalazine (Standard) is an orally active prodrug of 5-ASA (HY-15027). Olsalazine (Standard) can inhibit cells proliferation and induce apoptosis. Olsalazine (Standard) can reduce DAI and MPO activity and inhibit inflammatory cytokines levels. Olsalazine (Standard) can be used for the researches of cancer, inflammation and metabolic disease, such as colorectal cancer, inflammatory bowel disease (IBD) and hyperuricemic .
Target:
Research Areas:
Olsalazine Disodium (Standard) is an orally active prodrug of 5-ASA (HY-15027). Olsalazine Disodium (Standard) can inhibit cells proliferation and induce apoptosis. Olsalazine Disodium (Standard) can reduce DAI and MPO activity and inhibit inflammatory cytokines levels. Olsalazine Disodium (Standard) can be used for the researches of cancer, inflammation and metabolic disease, such as colorectal cancer, inflammatory bowel disease (IBD) and hyperuricemic .
Cat. No.: HY-167706
CAS No.: 53882-13-6
Target:
Research Areas:
Diethyl-Lodoxamide is a highly potent GPR35 agonist with potential to inhibit inflammatory bowel disease. Diethyl-Lodoxamide activates GPR35 in humans, mice and rats, showing similar EC50 values. Diethyl-Lodoxamide can alleviate the clinical symptoms of DSS-induced inflammatory bowel disease in mouse models, and the effect is better than the traditional drug 5-ASA. The pharmaceutical properties of Diethyl-Lodoxamide have been optimized to better meet the requirements of drug design .
Cat. No.: HY-B0174AS
Cat. No.: HY-B0174AS2
Synonyms: N-Acetyl-5-aminosalicylic acid (Standard); N-Acetyl-ASA (Standard)
Target:
Research Areas:
N-Acetyl mesalazine (Standard) (N-Acetyl-5-aminosalicylic acid (Standard)) is the analytical standard of N-Acetyl mesalazine (HY-66008). This product is intended for research and analytical applications. N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer .
Cat. No.: HY-145453R
CAS No.: 66532-85-2
Research Areas:
Propacetamol (Standard) is the analytical standard of Propacetamol (HY-145453). This product is intended for research and analytical applications. Propacetamol is an orally active prodrug of Acetaminophen (HY-66005), which exerts antipyretic and analgesic effects after metabolism. Propacetamol reduces Aspirin (ASA) (HY-14654)-induced elevation of malondialdehyde (MDA) in gastric mucosa and plasma, regulates the levels of gastric mucosal glutathione (GSH and GSSG) to maintain cellular antioxidant defense, and increases gastric mucosal uric acid (UA) levels. Propacetamol exerts a dose-dependent protective effect against ASA-induced gastric mucosal damage in rats. Propacetamol can be used for the study of gastric mucosal injury by interfering with oxidative stress .
Cat. No.: HY-15027S3
Synonyms: Mesalamine-d3 disodium; 5-ASA-d3 disodium; Mesalazine-d3 disodium
Cat. No.: HY-66008S
CAS No.: 93968-79-7
Synonyms: N-Acetyl-5-aminosalicylic acid-d3; N-Acetyl-ASA-d3
Cat. No.: HY-66008S1
CAS No.: 1309935-89-4
Synonyms: N-Acetyl-5-aminosalicylic acid-d3-1; N-Acetyl-ASA-d3-1
Cat. No.: HY-164480
CAS No.: 1588866-45-8
Research Areas:
GTCpFE inhibits IKKα/β in the NF-κB pathway with anti-inflammatory activities and blocks p65 nuclear entry, which consists of Dimethyl fumarate (DMF) (HY-17363) linked to Aspirin (ASA) (HY-14654). GTCpFE exhibits selective anti-cancer stem-like cell (CSC) activity by reducing mammosphere growth and the CD44 + CD24 - immunophenotype. GTCpFE inhibits breast cancer stem cells, an important NFκB- and PGE2-dependent phenotype in aggressive cancers .
Cat. No.: HY-66008S2
CAS No.: 1261392-91-9
Synonyms: N-Acetyl-5-aminosalicylic acid-13C6; N-Acetyl-ASA-13C6
Cat. No.: HY-15027S2
CAS No.: 1189709-96-3
Synonyms: Mesalamine-13C6; 5-ASA-13C6; Mesalazine-13C6
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
