62 Results for "

CD22

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "CD22" in MCE Product Catalog:

Cat. No.: HY-P990506
Synonyms: NCI m971

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-Siglec-2/CD22 Antibody (NCI m971) is a humanized antibody expressed in CHO cells that targets Siglec-2/CD22. Anti-Siglec-2/CD22 Antibody (NCI m971) features a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 146.64 kDa. The isotype control for Anti-Siglec-2/CD22 Antibody (NCI m971) can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990930
CAS No.: 2852752-92-0
Synonyms: AB-125
HY-P990930 is an CD22-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-184482
CAS No.: 1019642-47-7
Synonyms: BPC-Sia-LacNAc-N3
Target:  

Drug Intermediate

Research Areas:  

Cancer

CD22L-N3 (BPC-Sia-LacNAc-N3) is a pharmaceutical intermediate that can be used to synthesize CD22-specific trisaccharide ligands. CD22L-N3 is applicable to the research of B-cell lymphoma .
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Cat. No.: HY-171172
CAS No.: 2493080-16-1
Target:  

CD22

Research Areas:  

Inflammation/Immunology Cancer

GSC-718 is a CD22 inhibitor with an IC50 of 0.161 μM against mouse CD22. GSC-718 competitively blocks the binding of mouse CD22 to natural glycan ligands, and inhibits the interaction between CD22 and α2,6-sialylated ligands. GSC-718 promotes B cell proliferation and enhances antibody production. GSC-718 can be used in the research of B cell lymphoma and rheumatoid arthritis .
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Cat. No.: HY-P990507
Synonyms: NCI m972

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

The Anti-Siglec-2/CD22 Antibody (NCI m972) is a humanized antibody expressed in CHO, targeting Siglec-2/CD22. The Anti-Siglec-2/CD22 Antibody (NCI m972) has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 144.3 kDa. The isotype control for Anti-Siglec-2/CD22 Antibody (NCI m972) can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P75627
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: B-cell receptor CD22; BL-CAM; CD22; T-cell surface antigen Leu-14
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P75626
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: B-cell receptor CD22; BL-CAM; CD22; T-cell surface antigen Leu-14
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P704294
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704302
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70560
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-175320
Research Areas:  

Cancer

PROTAC c-Met degrader-5 is an orally active c-Met PROTAC degrader. PROTAC c-Met degrader-5 induces c-Met degradation via Cullin-CRBN, with a DC50 value of 0.32 nM, and inhibits the phosphorylation of c-Met and its downstream signaling molecule STAT3. PROTAC c-Met degrader-5 inhibits cancer cell proliferation, migration and invasion, induces apoptosis, alters cell cycle distribution, and suppresses the growth of EBC-1 xenograft tumors. PROTAC c-Met degrader-5 can be used to study MET-driven cancers as well as Tepotinib (HY-14721)-resistant cancers harboring c-Met D1228N and c-Met Y1230H mutations .
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Cat. No.: HY-P72474A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78641
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P75430
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P75431
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P701288
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P9959A
CAS No.: 635715-01-4
Synonyms: CMC-544 (solution); PF-5208773 (solution); WAY-207294 (solution)
Research Areas:  

Cancer

Inotuzumab ozogamicin solution (CMC-544 solution) is an antibody-targeted chemotherapy agent composed of a humanized anti-CD22 antibody conjugated to Calicheamicin (HY-19609). Inotuzumab ozogamicin solution and G544 bind human CD22 with similar affinities (Kd ≈ 150 pM). Inotuzumab ozogamicin solution has demonstrated efficacy against CD22 + B-cell non-Hodgkin’s lymphoma. Inotuzumab ozogamicin solution can be used in the research of acute lymphoblastic leukemia .
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Cat. No.: HY-P78541
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700895
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P73646
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD22; B-Lymphocyte Cell Adhesion Molecule; CD22 Molecule; T-Cell Surface Antigen Leu-14; SIGLEC2; BL-CAM; Sialic Acid-Binding Ig-Like Lectin 2; Sialic Acid Binding Ig-Like Lectin 2; B-Cell Receptor CD22; CD22 Protein; CD22 Antigen; Siglec-2; SIGLEC-2
Species:  
Mouse
Source:  
HEK293
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