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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
79 Results for "
Inactive ,metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (79)
79 Results for "Inactive ,metabolite" in MCE Product Catalog:
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Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting .
Cat. No.: HY-126373S1
Synonyms: SN-38G-13C6
Cat. No.: HY-126619
CAS No.: 71968-02-0
Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that is initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml.2 Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s=0.49 and 1.9 μg/mL, respectively).
Cat. No.: HY-W059917
CAS No.: 1300690-48-5
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AP24600 is an inactive metabolite of Ponatinib .
Cat. No.: HY-N0929R
CAS No.: 36062-05-2
Category:
Synonyms: 11-dehydro-2,3-dinor TXB2
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11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Item No. 19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.
Cat. No.: HY-W929472
CAS No.: 87984-82-5
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Drug Metabolite PPAR NOD-like Receptor (NLR) NF-κB Reactive Oxygen Species (ROS) Autophagy Caspase TNF Receptor NO Synthase Interleukin Related Apoptosis
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13 (S)-HOTrE is an oxylipin metabolite of α-Linolenic acid (HY-N0728). 13 (S)-HOTrE mediates the inactivation of the NLRP3 inflammasome through the PPAR-γ pathway to exert anti-inflammatory effects. 13 (S)-HOTrE inhibits NF-κB nuclear translocation, ROS production, autophagy and IL-1β levels, induces apoptosis, and increases IL-10 levels. 13 (S)-HOTrE alleviates LPS-induced inflammatory responses in macrophages, prolongs the survival time of septic mice, and regulates the immunometabolic phenotype in parenteral nutrition mouse models. 13 (S)-HOTrE can be used in the research of immune and inflammation-related diseases .
Cat. No.: HY-W704031
CAS No.: 239466-86-5
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Prasugrel metabolite 1 (M7 (R-119251)) is one of the inactive metabolites of Prasugrel (HY-15284) in the human body .
Cat. No.: HY-135500
CAS No.: 1433875-14-9
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ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist .
Cat. No.: HY-Z4483
CAS No.: 104227-86-3
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6-Deoxypenciclovir is an inactive metabolite of the antiviral prodrug Famciclovir. 6-Deoxypenciclovir is a good substrate for rabbit hepatic aldehyde oxidase and can be used to synthesize the prodrug form of penciclovir .
Cat. No.: HY-134520
CAS No.: 13649-88-2
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21-Deacetoxy deflazacort is a dehydrogenated derivative of Deflazacort (HY-13609), a glucocorticoid, an inactive precursor that is rapidly converted to the active metabolite 21-Desacetyldeflazacort. Deflazacort acts as an anti-inflammatory and immunosuppressant .
Cat. No.: HY-U00199
CAS No.: 59878-63-6
Synonyms: N-Desmethyl zopiclone; RP 32273
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Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.
Cat. No.: HY-125074
CAS No.: 368891-69-4
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PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic Linezolid (HY-10394).
Cat. No.: HY-W740674
CAS No.: 27046-19-1
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4-Ketocyclophosphamide is an inactive metabolite of the alkylating agent Cyclophosphamide (HY-17420).
Cat. No.: HY-118247
CAS No.: 110675-48-4
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Ro 14-6113 is an inactive phenolic metabolite of the "carotenoid" Ro 15-0778, a form of vitamin A.
Cat. No.: HY-W585982
CAS No.: 267244-08-6
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Bisphenol A-β-D-glucuronide is an inactive metabolite of the plasticizer Bisphenol A (HY-18260) .
Cat. No.: HY-132186
CAS No.: 384380-52-3
Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor Abacavir (HY-17423) .
Cat. No.: HY-135580
CAS No.: 84541-38-8
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Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent .
Cat. No.: HY-135580A
CAS No.: 84541-36-6
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Raloxifene Bismethyl Ether hydrochloride is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
