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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
LPC
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "LPC" in MCE Product Catalog:
Cat. No.: HY-126233A
CAS No.: 2650082-35-0
Target:
Research Areas:
PAT-347 sodium is an Autotaxin (ATX) inhibitor. ATX is a secretory enzyme that hydrolyzes lysophosphatidylcholine (LPC) and regulates lysophosphatidic acid (LPA) production in the blood .
Cat. No.: HY-187855
CAS No.: 17364-19-1
Synonyms: 18:0-LPC
Cat. No.: HY-119601
CAS No.: 313685-55-1
Target:
Research Areas:
GRI918013 (compound 1) is a selective and competitive autotaxin (ATX/NPP2) inhibitor with anti-invasive and anti-metastatic activity. GRI918013 competitively binds to ATX, blocking lipid substrates such as lysophosphatidylcholine (LPC) from entering the ATX active site, thereby inhibiting ATX-mediated hydrolysis of LPC to lysophosphatidic acid (LPA), and consequently inhibiting ATX-LPA axis-related tumor cell invasion and metastasis. GRI918013 inhibits ATX-mediated hydrolysis of the LPL substrate FS-3 (IC50=31.42 nM, Ki=12.98 nM). GRI918013 can be used in research on cancer invasion and metastasis, such as melanoma, and can also serve as a tool compound for ATX-LPA axis-related diseases such as fibrotic diseases, neuropathic pain, and cholestatic pruritus .
Cat. No.: HY-P82966
Synonyms: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
Cat. No.: HY-P700657
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANXA1; Annexin-1; Prev. ANX1; Annexin I (Lipocortin I); Prev. LPC1; ANXA1 Protein; Phospholipase A2 Inhibitory Protein; Lipocortin I; Chromobindin-9; Annexin I; Calpactin II; Annexin; Calpactin-2; P35; Annexin A1; Epididymis Secretory Sperm Binding Protei
Species:
Cynomolgus
Source:
E. coli
Cat. No.: HY-P71713
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANXA1; Annexin-1; Prev. ANX1; Annexin I (Lipocortin I); Prev. LPC1; ANXA1 Protein; Phospholipase A2 Inhibitory Protein; Lipocortin I; Chromobindin-9; Annexin I; Calpactin II; Annexin; Calpactin-2; P35; Annexin A1; Epididymis Secretory Sperm Binding Protei
Species:
Mouse
Source:
P. pastoris
Cat. No.: HY-P82966A
Synonyms: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
Cat. No.: HY-P790076
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX6; PRX; Peroxiredoxin 6; P29; AiPLA2; Red Blood Cells Page Spot 12; NSGPx; Lyso-PC Acyltransferase 5; AOP2; LPC Acyltransferase 5; Acidic Calcium-Independent Phospholipase A2; Antioxidant Protein 2; Lysophosphatidylcholine Acyltransferase 5; Liver 2D
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P811936
Synonyms: AGPAT11, AYTL1, LPCAT2, Lysophosphatidylcholine acyltransferase 2, LPC acyltransferase 2, LPCAT-2, LysoPC acyltransferase 2, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-acylglycerophosphocholine O-acyltransferase, 1-alkenylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acyltransferase-like 1, Lysophosphatidic acid acyltransferase alpha, 1-AGP acyltransferase 11, 1-AGPAT 11, Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT, LPAAT-alpha
Cat. No.: HY-P811936A
Synonyms: AGPAT11, AYTL1, LPCAT2, Lysophosphatidylcholine acyltransferase 2, LPC acyltransferase 2, LPCAT-2, LysoPC acyltransferase 2, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-acylglycerophosphocholine O-acyltransferase, 1-alkenylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acyltransferase-like 1, Lysophosphatidic acid acyltransferase alpha, 1-AGP acyltransferase 11, 1-AGPAT 11, Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT, LPAAT-alpha
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
