50 Results for "

NLS

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "NLS" in MCE Product Catalog:

Cat. No.: HY-174793
Target:  

mRNA

Research Areas:  

Others

The Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and a green fluorescent protein (GFP), which could be used in genome engineering experiments. The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.
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Cat. No.: HY-P10600
CAS No.: 1105053-46-0
Target:  

Ras

Research Areas:  

Others

BIMAX2 is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence .
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Cat. No.: HY-P11948
CAS No.: 253328-16-4
Target:  

c-Myc

Research Areas:  

Others

c-Myc NLS is a non-canonical nuclear localization signal (NLS) derived from the oncoprotein c-Myc, with the sequence PAAKRVKLD and containing 3 basic amino acids. c-Myc NLS mediates the nuclear localization of fusion proteins, and all its regions are essential or play important roles in nuclear import. c-Myc NLS can target fused pyruvate kinase to the nuclei of transfected cells .
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Cat. No.: HY-P11948A
Target:  

c-Myc

Research Areas:  

Others

c-Myc NLS TFA is a non-canonical nuclear localization signal (NLS) derived from the oncoprotein c-Myc, with the sequence PAAKRVKLD and containing 3 basic amino acids. c-Myc NLS TFA mediates the nuclear localization of fusion proteins, and all its regions are essential or play important roles in nuclear import. c-Myc NLS TFA can target fused pyruvate kinase to the nuclei of transfected cells .
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Cat. No.: HY-P3657A
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Biotin-KKKRKV acetate is the biotinylated KKKRKV acetate. KKKRKV is a nuclear localization signal (NLS) peptide derived from simian virus 40 .
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Cat. No.: HY-174792
Target:  

mRNA

Research Areas:  

Others

The Cre-T2A-GFP mRNA is a capped and polyadenylated messenger RNA encoding a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP).
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Cat. No.: HY-P11947
CAS No.: 254103-71-4
Target:  

MDM-2/p53 NF-κB

Research Areas:  

Others

p53 Bipartite NLS is a bipartite nuclear localization signal derived from p53. When p53 Bipartite NLS is fused to the N-terminus of p65 and the single-component nuclear localization signal of p65 itself is mutated, it alters the nuclear import pathway of p65. p53 Bipartite NLS renders p65 resistant to TTP (HY-P60128)-mediated inhibition of NF-κB transcriptional activity and nuclear import .
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Cat. No.: HY-172713
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-172714A
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-172715
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-P11662
CAS No.: 521076-75-5
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

NLS peptide is a nuclear localization signal peptide, a short amino acid sequence that can be recognized by nuclear transport machinery (such as the Importin protein complex). NLS peptide can directionally transport the molecules or nanoparticles linked to it into the nucleus, and the N-terminal Cys terminus can be used for subsequent coupling. NLS peptide can be used to construct nucleus-specific imaging probes and nucleus-targeted nanoparticles
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Cat. No.: HY-P1876D
CAS No.: 1818224-73-5
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Cys-NLS is a cysteine-containing nuclear localization signal peptide derived from the simian virus 40 large T antigen, which enhances nuclear import. Cys-NLS can undergo a coupling reaction through the common backbone of Cys .
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Cat. No.: HY-P11639
CAS No.: 380480-77-3
Research Areas:  

Others

ppTG21 is an endosomolytic agent and inducer. ppTG21 can facilitate endosomal escape of Cas9-2lig-1NLS and Cas9-ASGPrL ribonucleoproteins (RNPs) to enable receptor-facilitated, cell-type specific gene editing in cancer cells without electroporation or transfection reagents. ppTG21 can be used for the research of gene editing .
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Cat. No.: HY-111178R
CAS No.: 90280-13-0
Synonyms: BisfluoroModafinil (Standard); CRL-40940 (Standard); NLS-4 (Standard)
Research Areas:  

Neurological Disease

Lauflumide (Standard) is the analytical standard of Lauflumide (HY-111178). This product is intended for research and analytical applications. Lauflumide (BisfluoroModafinil) is the common alternative of modafinil. Modafinil is commonly prescribed for the research narcolepsy. Lauflumide has the potential for cognitive enhancing .
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Cat. No.: HY-182566
CAS No.: 288246-59-3
Target:  

HIV

Research Areas:  

Infection

ITI-367 is a HIV-1 inhibitor that targets the nuclear localization signal 1 (NLS-1) of HIV-1 matrix protein and the interaction between HIV-1 pre-integration complex (PIC) and importin-β. ITI-367 inhibits HIV-1 replication at the pre-integration stage, reduces the formation of 2-LTR circles, and sequesters viral DNA in the cytoplasm. ITI-367 can be used for the research of HIV infection .
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Cat. No.: HY-174791
Target:  

mRNA

Research Areas:  

Others

The Cre-T2A-GFP mRNA is a capped and polyadenylated messenger RNA encoding a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP). The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.
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Cat. No.: HY-P87288
Synonyms: 3 PGDH antibody; 3-PGDH antibody; 3-phosphoglycerate dehydrogenase antibody; 3PGDH antibody; D-3-phosphoglycerate dehydrogenase antibody; EC 1.1.1.95 antibody; Epididymis secretory protein Li 113 antibody; HEL S 113 antibody; NLS antibody; NLS1 antibody

Host:  

Mouse

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-172714
Target:  

Liposome

Research Areas:  

Infection

DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
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Cat. No.: HY-P705961
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPy_1046; csn1; cas9; SpyCas9; SpCas9; EC:3.1.-.- ; CRISPR-associated endonuclease Cas9/Csn1
Source:  
E. coli
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