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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
49 Results for "
Neutral pH
" in MedChemExpress (MCE) Product Catalog:
Products (49)
49 Results for "Neutral pH" in MCE Product Catalog:
Synonyms: S-303 dihydrochloride
Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .
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Hexokinase, microorganism is a hexokinase derived from microorganisms. It catalyzes the phosphorylation of glucose at the C6 position using ATP and Mg 2+, exhibits broad substrate specificity, and demonstrates thermal stability under neutral to weakly alkaline pH and high-temperature conditions. Hexokinase, microorganism uses ATP as the primary phosphate donor for sugar phosphorylation reactions. Hexokinase, microorganism belongs to the prokaryotic hexokinase family and catalyzes sugar phosphorylation reactions in carbohydrate metabolism .
Cat. No.: HY-D1457
CAS No.: 152584-38-8
Cat. No.: HY-DY1061
CAS No.: 158757-84-7
Solvent and concentration: DMSO: 2 mM
Cat. No.: HY-D2465
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CY5-Dextran (MW60-80k) is a fluorescent probe formed by covalent conjugation of the cyanine dye Cy5 to dextran. It is a pH-insensitive fluid-phase endocytosis tracer (the pH of endosomal lumen is precisely quantified by the fluorescence ratio of FITC/Cy5). CY5-Dextran (MW60-80k) is internalized by cells via a clathrin-independent fluid-phase pinocytosis pathway, and is sequentially evidenced by early endosomes, late endosomes are transported to lysosomes. CY5-D I cannot pass through the limited pore size formed by uncoating of human rhinovirus type 2 (HRV2), but can be released into the neutral cytoplasm upon adenovirus-mediated endosomal rupture, thus distinguishing between the two viral modes of "pore-forming escape" and "lysis escape". CY5-Dextran (MW60) -80k) has an excitation wavelength of 635 nm, and it can also be used for time-lapse imaging of endocytosis dynamics of stromal cells in tissues such as rat salivary glands under in vivo two-photon microscopy .
Synonyms: FAGLA
FA-Gly-Leu-NH2 (FAGLA) is a dipeptide substrate for proteases that can be hydrolyzed by thermophilic proteases and neutral proteases, showing pH-dependent variations in kcat/Km .
Cat. No.: HY-P5174
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Cat. No.: HY-W251598I
CAS No.: 144-55-8
Synonyms: Sodium hydrogen carbonate, meets analytical specification of pH. Eur., BP, USP, FCC, E500
Cat. No.: HY-P11309
CAS No.: 957365-81-0
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Cat. No.: HY-D1224A
CAS No.: 99792-50-4
Synonyms: CPRG sodium
Cat. No.: HY-135078
CAS No.: 17460-13-8
Synonyms: NSC 270912
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2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
Cat. No.: HY-P5172
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Cat. No.: HY-P11055
CAS No.: 2169935-95-7
Cat. No.: HY-155754
CAS No.: 90290-58-7
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3’-Acetate-ATP, an ATP analogue, is ATP acetylation product with an maxima uv absorption at 259 nm in water at neutral pH. 3’-Acetate-ATP exerts a blocking effect on nucleic acid polymerization .
Cat. No.: HY-158190
Synonyms: Rose Bengal Medium
Salvizol (Bisdequalinium diacetate) is a chemotherapeutic agent with a broad spectrum of bactericidal activity, effective in the apical third of root canals. Salvizol possesses the ability to dissolve organic dentin matrix, facilitating mineralization and tubule exposure. Salvizol maintains a neutral pH, ensuring biological compatibility while exhibiting significant cleansing potency.
Cat. No.: HY-E70330
CAS No.: 70851-98-8
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Neutral Proteinase, Bacillus sp. is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
