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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
OGT
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "OGT" in MCE Product Catalog:
Target:
Research Areas:
OSMI-3 (Compound 2b) is a potent, long-lasting, and cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-3 increases detained intron splicing in cells .
Cat. No.: HY-17020R
CAS No.: 72599-27-0
Synonyms: N-Butyldeoxynojirimycin (Standard); NB-DNJ (Standard); OGT 918 (Standard)
Research Areas:
Miglustat (Standard) is the analytical standard of Miglustat. This product is intended for research and analytical applications. Miglustat (N-Butyldeoxynojirimycin) is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat can be used for the research of type I gaucher disease .
Cat. No.: HY-17020S
CAS No.: 1883545-56-9
Synonyms: N-Butyldeoxynojirimycin-d9; NB-DNJ-d9; OGT 918-d9
Cat. No.: HY-RS23010
Target:
Research Areas:
Ogt Rat Pre-designed siRNA Set A contains three designed siRNAs for Ogt gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-17020AR
CAS No.: 210110-90-0
Synonyms: N-Butyldeoxynojirimycin hydrochloride (Standard); NB-DNJ hydrochloride (Standard); OGT 918 hydrochloride (Standard)
Research Areas:
Miglustat (hydrochloride) (Standard) is the analytical standard of Miglustat (hydrochloride). This product is intended for research and analytical applications. Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat hydrochloride can be used for the research of type I gaucher disease .
Cat. No.: HY-100898R
CAS No.: 853929-59-6
Target:
Research Areas:
OGT 2115 (Standard) is the analytical standard of OGT 2115 (HY-100898). This product is intended for research and analytical applications. OGT 2115 is a potent, cell-permeable and orally active heparanase inhibitor with an IC50 of 0.4 μM. OGT 2115 has anti-angiogenic properties (IC50 of 1 μM). OGT 2115 also inhibits heparan sulfate degradation activity .
Cat. No.: HY-19272
CAS No.: 185843-61-2
Research Areas:
OGT-719 is a potent, orally active nucleoside analogue that targets the asialoglycoprotein receptor (ASGP-R). OGT-719 inhibits growth of metastatic colorectal tumors in the liver of nude mice. OGT-719 can be used for primary hepatocellular carcinoma and colorectal liver metastases research .
Cat. No.: HY-RS16577
Target:
Research Areas:
Ogt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ogt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W477597
CAS No.: 1349070-58-1
BZX2 is an irreversible covalent inhibitor of O-GlcNAc transferase (OGT) with an IC50 of <10 µM. BZX2 is cell-permeable but exhibits multiple off-target effects .
Cat. No.: HY-W699962
CAS No.: 137766-83-7
Target:
Research Areas:
Ac4GlcNAcF3 is a cell-permeable glycomimetic that can be recognized and utilized by OGT and is resistant to hydrolysis by OGA. GlcNAcF3, the active metabolite of Ac4GlcNAcF3, can be recognized by OGT as a substrate for peptide modification. Ac4GlcNAcF3 upregulates the level of cellular O-GlcNAc modification. Ac4GlcNAcF3 can be used in studies related to glycosylation regulation .
Cat. No.: HY-119738R
CAS No.: 1681056-61-0
Target:
Research Areas:
OSMI-1 (Standard) is the analytical standard of OSMI-1 (HY-119738). This product is intended for research and analytical applications. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .
Cat. No.: HY-P87524
Synonyms: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT
Cat. No.: HY-P705511
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: OGT; MGC22921; O-Linked N-Acetylglucosamine (GlcNAc) Transferase; FLJ23071; UDP-N-Acetylglucosamine--Peptide N-Acetylglucosaminyltransferase 110 KDa Subunit; CDNA FLJ61388, Highly Similar To UDP-N-Acetylglucosamine--PeptideN-Acetylglucosaminyltransferase
Species:
Human
Source:
E. coli
Cat. No.: HY-184176
Target:
Research Areas:
DBCO-PEG3-AP1867 is a bifunctional molecular building block that binds to FKBP12 F36V, and also a SPAAC-compatible reagent suitable for synthesizing O-GlcNAcylation-targeting chimeras (OGTACs) against c-Myc. DBCO-PEG3-AP1867 is applicable to cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
