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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
Pkd2
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "Pkd2" in MCE Product Catalog:
Cat. No.: HY-RS16302
Target:
Research Areas:
PKD2 Pig Pre-designed siRNA Set A contains three designed siRNAs for PKD2 gene (Pig), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13687R
CAS No.: 873225-46-8
Research Areas:
IKK 16 (Standard) is the analytical standard of IKK 16. This product is intended for research and analytical applications. IKK 16 hydrochloride is an orally active IKK inhibitor. IKK 16 hydrochloride shows IC50s of 40 nM, 70 nM, 200 nM, and 50 nM for IKK2, IKK complex, IKK1, and LRRK 2, respectively. IKK 16 hydrochloride is also a pan-PKD inhibitor, inhibiting PKD1, PKD2, and PKD3 with IC50s of 153.9, 115, and 99.7 nM, respectively. IKK 16 hydrochloride is also an ABCB1 inhibitor, interfering with the binding of ABCB1 to its substrates. IKK 16 hydrochloride protects against LPS (HY-D1056)-induced multiple organ dysfunction by reducing the acute inflammatory response induced by endotoxin exposure. IKK 16 hydrochloride can restore renal function and alleviate fibrosis in acute kidney injury. IKK 16 hydrochloride attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus (T2DM) by inhibiting the NF-κB pathway.
Cat. No.: HY-15528R
CAS No.: 1233533-04-4
kb NB 142-70 (Standard) is the analytical standard of kb NB 142-70. This product is intended for research and analytical applications. kb NB 142-70 is a potent PKD inhibitor, with IC50s of 28.3, 58.7 and 53.2 nM for PKD1, PKD2, and PKD3, respectively. kb NB 142-70 also has antitumor activity.
Cat. No.: HY-117051
CAS No.: 1046490-67-8
STA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
Cat. No.: HY-RS10594
Target:
Research Areas:
PKD2L1 Human Pre-designed siRNA Set A contains three designed siRNAs for PKD2L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705865
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PRKD2; Serine/Threonine-Protein Kinase D2; Protein Kinase D2; DKFZP586E0820; Pkd2; NPKC-D2; HSPC187; PRKD2 Protein
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P81917A
Synonyms: PRKD2; Pkd2; HSPC187; Serine/threonine-protein kinase D2; nPKC-D2
Cat. No.: HY-RS19475
Target:
Research Areas:
Prkd2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prkd2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11147
Target:
Research Areas:
PRKD2 Human Pre-designed siRNA Set A contains three designed siRNAs for PRKD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P811886
Synonyms: TRPP2, Pkd2, Polycystin-2, PC2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321, Transient receptor potential cation channel subfamily P member 2
Cat. No.: HY-P811886A
Synonyms: TRPP2, Pkd2, Polycystin-2, PC2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321, Transient receptor potential cation channel subfamily P member 2
Cat. No.: HY-P701071
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SPP1; Uropontin; Prev. BNSP; Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein; Prev. OPN; CDNA FLJ54682, Highly Similar To Osteopontin; Osteopontin; Secreted Phosphoprotein 1 Variant 6; Lnc-Pkd2-2-3; Bone Sialoprotein I; ETA-1
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P705067
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPP1; Uropontin; Prev. BNSP; Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein; Prev. OPN; CDNA FLJ54682, Highly Similar To Osteopontin; Osteopontin; Secreted Phosphoprotein 1 Variant 6; Lnc-Pkd2-2-3; Bone Sialoprotein I; ETA-1
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P706302
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-OPN; ¹⁵N-Osteopontin; ¹⁵N-Secreted Phosphoprotein 1; SPP1; Uropontin; Prev. BNSP; Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein; Prev. OPN; CDNA FLJ54682, Highly Similar To Osteopontin; Osteopontin; Secreted Phosphoprotein 1 Variant 6; Lnc-Pkd2-2-3; Bone Sialoprotein I; ETA-1
Species:
Bovine
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
