68 Results for "

S 12

" in MedChemExpress (MCE) Product Catalog:
Products (68)

68 Results for "S 12" in MCE Product Catalog:

Cat. No.: HY-79863
CAS No.: 868540-15-2
Domaines de recherche:  

Others

(6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate is a phenylalanine derivative .
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Cat. No.: HY-79334
CAS No.: 4254-15-3
(S)-(+)-1,2-Propanediol is an endogenous metabolite. (S)-(+)-1,2-Propanediol can be used as an organic solvent and diluent in drug preparations. (S)-(+)-1,2-Propanediol can also be used as a chiral synthetic intermediate and a substrate for enzyme research .
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Cat. No.: HY-107608S
CAS No.: 124629-74-9
Synonyms: LTB4-d4; 5(S),12(R)-DiHETE-d4
Leukotriene B4-d4 is the deuterium labeled Leukotriene B4. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-Z0028
CAS No.: 1541172-75-1
Synonyms: Carfilzomib Impurity 2
Target:  

Drug Intermediate

Domaines de recherche:  

Others

(S)-N-((S)-1-(((2R,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-RS12222
Domaines de recherche:  

Others

RPS12 Human Pre-designed siRNA Set A contains three designed siRNAs for RPS12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-79334R
CAS No.: 4254-15-3
(S)-(+)-1,2-Propanediol (Standard) is the analytical standard of (S)-(+)-1,2-Propanediol. This product is intended for research and analytical applications. (S)-(+)-1,2-Propanediol is an endogenous metabolite. (S)-(+)-1,2-Propanediol can be used as an organic solvent and diluent in drug preparations. (S)-(+)-1,2-Propanediol can also be used as a chiral synthetic intermediate and a substrate for enzyme research.
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Cat. No.: HY-90009C
CAS No.: 629652-72-8
Synonyms: ent-IC-351
Domaines de recherche:  

Cancer

ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS). compound (6R,12aS) is a potent PDE5 inhibitor with an IC50 of 0.090 μM, while ent-Tadalafil is inactive at concentrations up to 10 µM .
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Cat. No.: HY-W747548
CAS No.: 116180-17-7
Domaines de recherche:  

Inflammation/Immunology

12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
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Cat. No.: HY-W001968
CAS No.: 498-62-4
Synonyms: 3-TC
Target:  

Drug Intermediate

Domaines de recherche:  

Others

3-Thiophenecarboxaldehyde is a thiophene derivative substrate for biocatalytic reduction to 3-thiophenemethanol, and can be processed by Pseudomonas putida S12 cells. 3-Thiophenecarboxaldehyde functions as an intermediate compound. 3-Thiophenecarboxaldehyde exhibits toxicity toward Pseudomonas putida S12 cells at elevated concentrations, reducing specific growth rate and final biomass yield .
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Cat. No.: HY-90009D
CAS No.: 171596-28-4
Synonyms: Tadalafil EP Impurity C; (6S,12aR)-IC-351
Domaines de recherche:  

Cardiovascular Disease Metabolic Disease

(6S,12aR)-Tadalafil (Tadalafil EP Impurity C) is a highly potent PDE5 inhibitor with an IC50 value of 5 nM and has blood pressure lowering activity .
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Cat. No.: HY-N12962
CAS No.: 123931-40-8
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .
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Cat. No.: HY-N12962A
CAS No.: 123931-38-4
11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures .
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Cat. No.: HY-107608A
CAS No.: 79056-01-2
Synonyms: 5(S),12(S)-LTB4; 5(S),12(S)-DiHETE
Target:  

Others

Domaines de recherche:  

Others

5(S),12(S)-Leukotriene B4 (5(S),12(S)-LTB4; 5(S),12(S)-DiHETE) is a stereochemical isomer of LTB4 (HY-107608) .
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Cat. No.: HY-163514
Domaines de recherche:  

Neurological Disease

hAChE-IN-8 (Compound S-12) is a orally effective and selective inhibitor of hAChE (IC50=0.486 μM). hAChE-IN-8 also inhibits BACE-1 (IC50=0.542 μM), and does not inhibit Dyrk1A (IC50>10 μM). hAChE-IN-8 can reduce Aβ aggregation, has good blood-brain barrier penetration. hAChE-IN-8 is mainly used in Alzheimer's disease research .
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Cat. No.: HY-149154
CAS No.: 423769-22-6
Target:  

Antibiotic

Domaines de recherche:  

Infection

(4S,5S,6S,12aS)-Oxytetracycline is a broad-spectrum antibiotic that can inhibit the synthesis of protein in bacteria. (4S,5S,6S,12aS)-Oxytetracycline is an important member of the bacterial aromatic polyketone family, a type of natural product with diverse structures .
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Cat. No.: HY-N11490
CAS No.: 122677-90-1
(25S)-12β-Hydroxyspirost-4-en-3-one is a natural compound that can be isolated from Dioscorea chiupasensis .
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Cat. No.: HY-166064
CAS No.: 874393-57-4
Domaines de recherche:  

Metabolic Disease

Methyl 11(S),12(S)-epoxy-13(S)-hydroxy-9(Z),15(Z)-octadecadienoate is an ester product.
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Cat. No.: HY-125775
CAS No.: 148019-74-3
Synonyms: (12S)-12-Hydroxy-15-hexadecynoic acid
Domaines de recherche:  

Endocrinology

12(S)-Hydroxy-16-heptadecynoic acid ((12S)-12-Hydroxy-15-hexadecynoic acid) is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM.
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Cat. No.: HY-RS11328
Domaines de recherche:  

Others

PSMD7 Human Pre-designed siRNA Set A contains three designed siRNAs for PSMD7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06461
Domaines de recherche:  

Others

HTR1B Human Pre-designed siRNA Set A contains three designed siRNAs for HTR1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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