629652-72-8
Chemical Structure
ent-Tadalafil
Synonym(s): ent-IC-351
- CAS No.: 629652-72-8
- Formula:C22H19N3O4
- Molecular Weight:389.40
IUPAC Name: (6S,12aS)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
InChIKey: WOXKDUGGOYFFRN-KKSFZXQISA-N
SMILES: O=C([C@]1([H])CC2=C([C@H](C3=CC=C(OCO4)C4=C3)N15)NC6=C2C=CC=C6)N(C)CC5=O
Biological Activity: ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS). compound (6R,12aS) is a potent PDE5 inhibitor with an IC50 of 0.090 μM, while ent-Tadalafil is inactive at concentrations up to 10 µM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ent-Tadalafil | 98.17% | ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS). compound (6R,12aS) is a potent PDE5 inhibitor with an IC50 of 0.090 μM, while ent-Tadalafil is inactive at concentrations up to 10 µM. | ||||||||||||||||||||
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Keywords
