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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
elastin
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "elastin" in MCE Product Catalog:
Cat. No.: HY-P0063A
CAS No.: 300801-03-0
Synonyms: GHK-Cu acetate
Target:
Research Areas:
Copper tripeptide (GHK-Cu) acetate is a tripeptide. During wound healing, Copper tripeptide acetate may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide acetate has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide acetate is a natural modulator of multiple cllular pathways in skin regeneration .
Cat. No.: HY-P5270
CAS No.: 70592-18-6
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Cat. No.: HY-B0166E
CAS No.: 15431-40-0
Synonyms: L-Ascorbate magnesium; Vitamin C magnesium
Cat. No.: HY-136705
CAS No.: 111682-13-4
Synonyms: MSACK
Target:
Research Areas:
MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE), with an IC50 of 20.3 μM. MeO-Suc-Ala-Ala-Pro-Ala-CMK can inhibit the hydrolysis of substrates such as elastin in lung tissue by HNE. MeO-Suc-Ala-Ala-Pro-Ala-CMK can be used in the research of related diseases such as chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-171657
CAS No.: 411233-11-9
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4'-Acetoxy resveratrol is a Resveratrol (HY-16561) derivative. 4'-Acetoxy resveratrol upregulates gene expression of elastin, collagen types III and IV, superoxide dismutase (SOD), and catalase (CAT), while downregulating interleukins (IL-1A, IL-1R2, IL-6, IL-8) and cyclooxygenase-2 (COX-2) in human skin models. 4'-Acetoxy resveratrol can be used for skin reasearch .
Cat. No.: HY-P11550
CAS No.: 52231-42-2
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Cat. No.: HY-174719
Target:
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Human ELANE mRNA encodes the human elastase (ELANE) protein, a member of serine proteases family. ELANE may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin.
Cat. No.: HY-W014125R
CAS No.: 1852-04-6
Cat. No.: HY-P5279
CAS No.: 2228114-98-3
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Cat. No.: HY-P6183
CAS No.: 2672508-37-9
Cat. No.: HY-149205
CAS No.: 2919976-92-2
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Cat. No.: HY-B0130R
CAS No.: 82834-16-0
Synonyms: S-9490 (Standard)
Research Areas:
Perindopril (Standard) is the analytical standard of Perindopril. This product is intended for research and analytical applications. Perindopril (S-9490) is an orally available, long-acting angiotensin-converting enzyme (ACE) inhibitor. Perindopril inhibits inflammatory cell influx and intimal thickening, preserving elastin on the inside of the aorta. Perindopril effectively inhibits experimental abdominal aortic aneurysm (AAA) formation in a rat model and reduces pulmonary vasoconstriction in rats with pulmonary hypertension .
Cat. No.: HY-B0130S1
Synonyms: S-9490-d5
Cat. No.: HY-A0169
CAS No.: 33320-16-0
Research Areas:
Methyl aminolevulinate is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate is applicable to research related to actinic keratosis and basal cell carcinoma .
Cat. No.: HY-N12630
CAS No.: 65318-21-0
Synonyms: Mycosporine-Gly
Category:
Cat. No.: HY-W014125S
Cat. No.: HY-P705427
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ELN; WS; elastin; Supravalvular Aortic Stenosis; Tropoelastin; Williams-Beuren Syndrome; SVAS; ADCL1; WBS
Species:
Mouse
Source:
E. coli
Cat. No.: HY-K0612
MCE Weigert Elastin Staining Kit combines Weigert Resorcinol Fuchsin Staining Solution with Van Gieson (VG,Elastin Fiber Staining Reagent B,mixed) Staining Solution. Weigert Resorcinol Fuchsin Solution is mainly used for staining elastic fibers, Van Gieson (VG) Solution is used for collagen fiber staining. The principle of VG staining is based on differences in the size of anionic dye molecules and the permeability of tissues. Picric acid (PA) has the smallest molecular weight and preferentially enters dense structures. Ponceau Red or acid fuchsin has a relatively larger molecular weight and primarily binds to collagen fibers, while light green has the largest molecular weight and stains other tissue components. After VG staining, collagen fibers appear red, while muscle fibers and cytoplasm appear yellow, enabling a clear distinction between tissue components.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
