L-Ascorbic acid magnesium
Based on 1 Customer Validation
L-Ascorbic acid (L-Ascorbate) magnesium, an electron donor, is an endogenous antioxidant. L-Ascorbic acid selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition promoter and elastin production inhibitor. L-Ascorbic acid exhibits anticancer effects by generating reactive oxygen species (ROS) and selectively damaging cancer cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.50%
- CAS No.: 15431-40-0
- 화학식: C6H8O6.1/2Mg
- 분자량:187.27
-
보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
용액&용해도
- Protocol
- 순도&문서
- References
-
Help & FAQs
-
HY-W011180
Vitamin A Propionate -
HY-B0166A
L-Ascorbic acid sodium saltCalcium Channel Inhibitor -
HY-B1278B
(±)-α-Tocopherol acetateVitamin E Acetate -
HY-B1746
Pyridoxamine 5′-phosphateAntioxidant -
HY-32350
ErcalcitriolVDR Agonist -
HY-N6677
β-Apo-8'-carotenalCYP1A Inducer -
HY-32343
SecalciferolVitamin D Metabolite -
HY-32351A
Calcifediol monohydrateVDR Ligand -
HY-128742
Thiamine monophosphate chloride dihydrateThiamine Precursor -
HY-B1278BR
(±)-α-Tocopherol acetate (Standard)Vitamin E Acetate -
HY-B2212
Dibenzoyl ThiamineThiamine Derivative -
HY-W127530
α-Tocopherol phosphate disodiumAntioxidant Agent
Biological Activity
제품 설명
Chemical Information
-
CAS No. 15431-40-0
-
Appearance Solid
-
분자량 187.27
-
화학식 C6H8O6.1/2Mg
-
Color White to light yellow
-
SMILES
OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O.[0.5Mg2+]
-
Synonyms
L-Ascorbate magnesium; Vitamin C magnesium
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
H2O : 2.5 mg/mL (13.35 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
-
Data Sheet (278 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35. [Content Brief]
[2]. Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J Neurosci. 2007 Nov 14;27(46):12577-83. [Content Brief]
[3]. Aleksander Hinek, et al. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75(3):173-82. [Content Brief]
[4]. Sungrae Cho, et al. Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression. Sci Rep. 2018 Jul 27;8(1):11372. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3399 mL | 26.6994 mL | 53.3988 mL | 133.4971 mL |
| 5 mM | 1.0680 mL | 5.3399 mL | 10.6798 mL | 26.6994 mL | |
| 10 mM | 0.5340 mL | 2.6699 mL | 5.3399 mL | 13.3497 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Ascorbic acid magnesium Related Classifications
HY-B0166E Related Classifications
Powered by Bioz