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United States

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Cat. No.: HY-P11550

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VPGVG

VPGVG is a repeating sequence that constitutes elastin-like peptides. VPGVG is derived from sequences found in the hydrophobic regions of vertebrate elastin. Elastin-like peptides are temperature-responsive biomaterials.

For research use only. We do not sell to patients.

CAS No.: 52231-42-2
Formula: C₁₉H₃₃N₅O₆
Molecular Weight:427.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

VPGVG Chemical Structure

CAS No.: 52231-42-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 52231-42-2
Molecular Weight 427.50
Formula C₁₉H₃₃N₅O₆
Sequence

Val-Pro-Gly-Val-Gly
Sequence Shortening

VPGVG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Histomorphology

Fibers: Elastic Fiber Staining
Elastic fiber staining is a histochemical technique used to selectively visualize elastin-rich structures such as elastic fibers in connective tissues (e. g. , blood vessels, lung, dermis) based on the affinity of specific dyes or oxidation products for elastin-associated amino acid residues and cross-linked elastic matrix components. Classical methods such as Verhoeff-Van Gieson (VVG), resorcin-fuchsin (Weigert-type stains), or aldehyde fuchsin rely on differential binding of dye complexes to elastic fibers, allowing them to be distinguished from collagen and other extracellular matrix components by contrast staining (typically black or deep purple elastic fibers against red collagen counterstain). These methods are widely used in histopathology to evaluate elastic fiber integrity, fragmentation, or remodeling in vascular diseases, pulmonary pathology, and connective tissue disorders.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Suyama K, et al. Azobenzene-Modified Temperature-Responsive Short Elastin-like Peptides for Photo-Controlled Phase Transition. ACS Synth Biol. 2025 Aug 15;14(8):2999-3012. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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