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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
sugar phosphate ester intermediate
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "sugar phosphate ester intermediate" in MCE Product Catalog:
Cat. No.: HY-111095S2
CAS No.: 1224440-85-0
Synonyms: (R)-2-Hydroxypropionic acid-13C-1; D-Lactic acid-13C-1
Cat. No.: HY-128753S7
Cat. No.: HY-128748R
CAS No.: 56-82-6
Cat. No.: HY-128753R
CAS No.: 1114-34-7
Cat. No.: HY-128753S3
CAS No.: 70849-22-8
Cat. No.: HY-128753S4
CAS No.: 83379-39-9
Cat. No.: HY-128753S5
CAS No.: 139657-61-7
Cat. No.: HY-W725496
CAS No.: 103213-47-4
Cat. No.: HY-113407C
Target:
Research Areas:
D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
Cat. No.: HY-E71497
Target:
Research Areas:
2-Dehydro-3-deoxy-D-arabinonate dehydratase (EC 4.2.1.141) participates in pentose oxidation pathways that convert pentose sugars to the tricarboxylic acid cycle intermediate 2-oxoglutarate.
Cat. No.: HY-113272A
CAS No.: 551-85-9
Synonyms: D-Ru5P
Target:
Research Areas:
D-Ribulose 5-phosphate is an important sugar phosphate that participates in multiple metabolic pathways. D-Ribulose 5-phosphate serves as an intermediate in the pentose phosphate pathway and also acts as a substrate for D-Arabinose 5-phosphate isomerase (GutQ/KdsD) .
Cat. No.: HY-156231
CAS No.: 2855124-81-9
Target:
Research Areas:
Glc-GlcNAc-oxazoline is a disaccharide intermediate that can introduce an azide side chain onto the sugar moiety. Glc-GlcNAc-oxazoline can be used in studies related to the synthesis of antibody-drug conjugates (ADC) via click chemistry .
Cat. No.: HY-113407CS
Target:
Research Areas:
L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism .
Cat. No.: HY-113407B
CAS No.: 918149-30-1
Target:
Research Areas:
D-Fructose 6-phosphate disodium hydrate is an endogenous metabolite. D-Fructose 6-phosphate disodium hydrate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium hydrate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium hydrate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate disodium hydrate can be used to study Lewy body dementia .
Cat. No.: HY-134902A
Synonyms: UDP-α-6N3-glucose disodium; 6-Azidoglucose-UDP disodium
Research Areas:
UDP-6-azido-6-Deoxy-D-Glc disodium (UDP-α-6N3-glucose; 6-Azidoglucose-UDP disodium) is a UDP-sugar donor . UDP-6-azido-6-Deoxy-D-Glc disodium is used for the selective labeling of 5-hmC in genomic DNA. UDP-6-azido-6-Deoxy-D-Glc disodium enables glyco-diversification modification of saponin intermediates and click chemistry-based derivatization .
Cat. No.: HY-L252
76 compounds
Carbohydrate metabolism serves as a central hub for energy supply and biosynthesis in living organisms and plays a critical role in the onset and progression of various diseases. In recent years, studies have shown that tumor cells reprogram their energy metabolism through aerobic glycolysis (the Warburg effect) to support rapid proliferation. Immune cells also rely on specific carbohydrate metabolic pathways to regulate their activation and differentiation states, while disorders such as diabetes and metabolic syndrome arise directly from dysregulation of carbohydrate metabolism. In addition, enzymes and key metabolic nodes involved in carbohydrate metabolism have become important targets for drug discovery, and therapeutic strategies targeting glycolysis, the pentose phosphate pathway, and energy metabolism are continuously advancing the treatment of cancer and metabolic diseases. Therefore, systematic analysis of carbohydrate metabolic networks and their associated metabolites is of great significance for elucidating disease mechanisms and developing novel therapeutic approaches.
The MCE Carbohydrate Metabolism Metabolite Library is constructed based on classical carbohydrate metabolic pathways and contains 76 metabolites. It systematically integrates key metabolic networks, including glycolysis, the pentose phosphate pathway, the tricarboxylic acid (TCA) cycle, monosaccharide metabolism, and sugar acid interconversions. The library comprehensively covers core metabolic nodes from glucose uptake and utilization to energy production and biosynthesis, while also incorporating important upstream and downstream intermediates. It enables accurate representation of intracellular metabolic flux dynamics and is well suited for applications such as metabolic flux analysis, target validation, and mechanistic studies. Furthermore, it provides robust support for multi-omics integration and the development of precision intervention strategies.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
