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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
CSK
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "CSK" in MCE Product Catalog:
Cat. No.: HY-P1405A
Synonyms: Pam3Cys-Ser-(Lys)4-Biotin TFA
Target:
Research Areas:
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R and Tie-2 with IC50 values of 0.24, 1.19, 10.74 and 5.85 µM, respectively. RK-20448 also inhibits BLK, Csk, Fyn and Lyn with IC50 values of 0.37, 4.27, 2.03 and 0.43 µM, respectively. RK-20448 is the cis isomer of A-419259 (HY-15764) .
Cat. No.: HY-156745
CAS No.: 3036944-98-3
PROTAC DDa-1 is a multi-targeted DCAF1-recruiting tyrosine kinase PROTAC degrader. PROTAC DDa-1 mediates the degradation of TNK2, CSK, LIMK2, TEC, and BTK, with a DC50 of 90 nM for BTK. PROTAC DDa-1 reduces the viability of BTK-dependent diffuse large B-cell lymphoma cells. PROTAC DDa-1 can be used for the research of diffuse large B-cell lymphoma .
Cat. No.: HY-P10527
Cat. No.: HY-RS03238
Target:
Research Areas:
CSK Human Pre-designed siRNA Set A contains three designed siRNAs for CSK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5527F
Target:
Research Areas:
Cat. No.: HY-W114420
CAS No.: 17028-03-4
Target:
Research Areas:
3-Methyl-L-tyrosine is a derivative of L-Tyrosine (HY-N0473). Structurally, 3-Methyl-L-tyrosine features a methyl modification at the third position of the aromatic ring of L-Tyrosine. As a substrate for the protein tyrosine kinase Csk, 3-Methyl-L-tyrosine's relative catalytic efficiency (kcat/Km) is 38% of L-Tyrosine, indicating that the methyl modification impacts the processing efficiency of Gsk significantly. 3-Methyl-L-tyrosine helps to deepen the understanding of Gsk's molecular recognition mechanisms of its substrates, which is crucial for developing specific inhibitors targeting Gsk .
Cat. No.: HY-RS16760
Target:
Research Areas:
Csk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23199
Target:
Research Areas:
Csk Rat Pre-designed siRNA Set A contains three designed siRNAs for Csk gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P75322
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSK; Protein-Tyrosine Kinase CYL; C-Terminal Src Kinase; C-Src Tyrosine Kinase; CSK, Non-Receptor Tyrosine Kinase; C-Src Kinase; Tyrosine-Protein Kinase CSK; Tyrosine-Protein Kinase
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P72957
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CSK; Protein-Tyrosine Kinase CYL; C-Terminal Src Kinase; C-Src Tyrosine Kinase; CSK, Non-Receptor Tyrosine Kinase; C-Src Kinase; Tyrosine-Protein Kinase CSK; Tyrosine-Protein Kinase
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P72956
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSK; Protein-Tyrosine Kinase CYL; C-Terminal Src Kinase; C-Src Tyrosine Kinase; CSK, Non-Receptor Tyrosine Kinase; C-Src Kinase; Tyrosine-Protein Kinase CSK; Tyrosine-Protein Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P85546
Synonyms: C SRC; C SRC kinase; C src Tyrosine Kinase; C-SRC kinase; c-src tyrosine kinase; CSK A; CSK; CSK_HUMAN; CYTOPLASMIC TYROSINE KINASE; MGC112926; MGC117393; MGC154049; P60 Src; Protein tyrosine kinase CYL; Protein-tyrosine kinase CYL; Proto oncogene tyrosine protein kinase; Tyrosine protein kinase CSK; Tyrosine protein kinase CSK; Tyrosine-protein kinase CSK; zgc:154049.
Cat. No.: HY-18909
CAS No.: 1157857-36-7
Multi-kinase-IN-11 (Compound 1a) is a DFG-out conformation-targeted multi-kinase inhibitor, including SRC, LCK, ABL, PYK2, CSK, HCK, P38 and C-KIT. Multi-kinase-IN-11 serves as a scaffold for the preparation of fluorescently labeled binding probes and affinity matrices .
Cat. No.: HY-187341
Research Areas:
CSF1R/c-Kit-IN-2 is a dual CSF-1R/c-Kit inhibitor with a c-Kit-biased profile, exhibiting inhibitory activity against CSF-1R (IC50 = 6.84 nM), c-Kit (IC50 = 0.95 nM), FYN (IC50 = 11.4 nM), ABL1 (IC50 = 14.2 nM), and CSK (IC50 = 118 nM). CSF1R/c-Kit-IN-2 can be used for the research of neuroinflammation-associated neurodegenerative diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
