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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
DP2
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "DP2" in MCE Product Catalog:
Cat. No.: HY-135208
CAS No.: 916048-02-7
Target:
Domaines de recherche:
tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate is an intermediate used in the synthesis of potent DP2 receptor antagonists based on a novel spiro-indolinone compound .
Cat. No.: HY-15950R
CAS No.: 802904-66-1
Target:
Domaines de recherche:
AZD1981 (Standard) is the analytical standard of AZD1981. This product is intended for research and analytical applications. AZD1981 is the antagonist for GPR44 (also known also PTGDR2, DP2 or CRTh). AZD1981 blocks the binding of PGD2 to CRTH2. AZD1981 exhibits immunomodulatory effects and can be used in research of chronic spontaneous urticaria [2].
Cat. No.: HY-126911
CAS No.: 62145-07-7
Synonyms: Fluprostenol Prostaglandin D2
Target:
Domaines de recherche:
11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.
Cat. No.: HY-A0095B
CAS No.: 147359-76-0
Synonyms: BIMT-17 hydrochloride; BIMT-17BS hydrochloride
Target:
Domaines de recherche:
Flibanserin (BIMT-17) hydrochloride is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin hydrochloride shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
Synonyms: 15-Deoxy-Δ12,14-PGD2
Domaines de recherche:
15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2) is a metabolite of prostaglandin D₂ (PGD₂) (HY-101988), which can undergo further dehydration metabolism to 15-deoxy-Δ12,14-PGJ₂. 15-deoxy-Δ12,14-Prostaglandin D2 is a highly selective agonist for DP2 receptor and PPARγ. 15-deoxy-Δ12,14-Prostaglandin D2 causes morphological changes in eosinophils and migration of type II innate lymphoid cells (ILC2). 15-deoxy-Δ12,14-Prostaglandin D2 has a growth inhibitory effect on prostate cancer cells expressing PPARγ, induces cell cycle arrest and promotes apoptosis. 15-deoxy-Δ12,14-Prostaglandin D2 can be used in related research on asthma and prostate cancer [2].
Cat. No.: HY-13213A
CAS No.: 1263077-74-2
Target:
Domaines de recherche:
AM211 sodium is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
Cat. No.: HY-109186A
CAS No.: 2155800-40-9
Target:
Domaines de recherche:
Pexopiprant L-lysine is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant L-lysine can be used in studies of asthma .
Cat. No.: HY-109186R
CAS No.: 932708-14-0
Domaines de recherche:
Pexopiprant (Standard) is the analytical standard of Pexopiprant (HY-109186). This product is intended for research and analytical applications. Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma .
Cat. No.: HY-116028S1
CAS No.: 2750534-91-7
Synonyms: 15-Deoxy-Δ12,14-PGD2-d4
Cat. No.: HY-RS14418
Target:
Domaines de recherche:
TFDP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TFDP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11371
Target:
Domaines de recherche:
PTGDR2 Human Pre-designed siRNA Set A contains three designed siRNAs for PTGDR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00807
Target:
Domaines de recherche:
APC Human Pre-designed siRNA Set A contains three designed siRNAs for APC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-16768R
CAS No.: 872365-14-5
Synonyms: QAW039 (Standard); NVP-QAW039 (Standard)
Domaines de recherche:
Fevipiprant (Standard) is the analytical standard of Fevipiprant. This product is intended for research and analytical applications. Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma [2] .
Cat. No.: HY-E70316
Target:
Domaines de recherche:
Endo-chitosanase is an endochitosanase belonging to the GH46 family that catalyzes chitosan substrate to produce chitobiose and D-glucosamine (GlcN). Endo-chitosanase acts in a stochastic intra-action manner, producing chitosan derivatives with different degrees of polymerization (DP) ≤2 .
Cat. No.: HY-116811
CAS No.: 629645-40-5
Domaines de recherche:
AZ-11665362 is a CRTh2 (DP2) receptor antagonist with an IC50 of 2.6 nM. AZ-11665362 shows weak activity against aldose reductase, serotonin transporter, CYP 2C19, and CYP 2C9. AZ-11665362 lacks measurable inhibitory activity against COX-1 and COX-2. AZ-11665362 can be used for the research of asthma, and other inflammatory diseases .
Cat. No.: HY-P991837
Target:
Domaines de recherche:
Cat. No.: HY-126773
CAS No.: 741250-22-6
Target:
Domaines de recherche:
Dp2mT is a non-cytotoxic control compound, with an IC50 of >3 μM for HIV-1 transcription inhibition and an IC50 of >10 μM for cytotoxicity. Dp2mT does not bind to intracellular iron pools. Dp2mT does not inhibit CDK9 activity .
Cat. No.: HY-A0095AS
CAS No.: 2748630-46-6
Synonyms: BIMT-17-d4 hydrochloride; BIMT-17BS-d4 hydrochloride
Cat. No.: HY-A0095R
CAS No.: 167933-07-5
Synonyms: BIMT-17 (Standard); BIMT-17BS (Standard)
Target:
Domaines de recherche:
Flibanserin (Standard) is the analytical standard of Flibanserin. This product is intended for research and analytical applications. Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
Cat. No.: HY-A0095S
CAS No.: 2122830-90-2
Synonyms: BIMT-17-d4; BIMT-17BS-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
