509 Results for "

CD3+

" in MedChemExpress (MCE) Product Catalog:
Products (509)

509 Results for "CD3+" in MCE Product Catalog:

Cat. No.: HY-P990759
CAS No.: 2795115-07-8
Synonyms: JNJ-75348780

Target:  

CD22 CD3

Research Areas:  

Inflammation/Immunology

Rezetamig is a human bispecific antibody that recognizes the CD3 antigen on T-lymphocytes and the CD22 antigen on mature and malignant B-lymphocytes .
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Cat. No.: HY-P991163
CAS No.: 2969220-04-8

Target:  

CD3 Claudin

Research Areas:  

Cancer

Tixentamig is a bispecific monoclonal antibody targeting human CD3 ε and CLDN18 (claudin 18). Tixentamig is promising for research of cancers .
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Cat. No.: HY-P991842
Anti-CD3 Antibody (UCHT-1) is an antibody targeting CD3. Anti-CD3 Antibody (UCHT-1) activates the phospholipase C and phosphatidylinositol 3-kinase (PI3K) signaling pathways, elevates intracellular calcium levels, regulates the T3 epitope, and triggers T lymphocyte proliferation. Anti-CD3 Antibody (UCHT-1) also inhibits lymphocyte proliferation, abolishes IL-2 production, and blocks the expression of IL-2 receptors. Anti-CD3 Antibody (UCHT-1) is applicable to research related to graft-versus-host disease, acute myeloid leukemia, and B-cell acute lymphoblastic leukemia [3] .
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Cat. No.: HY-P99837
CAS No.: 2367001-71-4
Synonyms: SPV-T3a

Target:  

CD3

Research Areas:  

Infection

Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .
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Cat. No.: HY-P990928
CAS No.: 2839556-21-5
Synonyms: APVO-436

Target:  

CD3 Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Mipletamig (APVO-436) is a bispecific CD123 x CD3 monoclonal antibody. Mipletamig simultaneously binds to both CD3-expressing T cells and CD123-expressing cancer cells, thereby crosslinking CD123-expressing tumor cells and cytotoxic T lymphocytes (CTLs). This results in the activation and proliferation of T-cells and causes CTL-mediated cell lysis of CD123-expressing tumor cells. Mipletamig can be used for the study of acute myeloid leukemia (AML) .
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Cat. No.: HY-P991479
CAS No.: 2839531-84-7
Synonyms: GS-8588

Target:  

HIV CD3

Research Areas:  

Infection

Amtabafusp alfa (GS-8588) is an envelope-targeting bispecific T-cell engager for HIV treatment. Amtabafusp alfa redirects effector T cells by binding to CD3 via a humanized anti-CD3 Fab domain and to HIV envelope proteins via an engineered CD4 domain 1 variant. Amtabafusp alfa exhibits potent, broad-spectrum activity against a variety of HIV isolates and specifically kills HIV-infected cells. Amtabafusp alfa can be used for research on HIV infection .
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Cat. No.: HY-176720
Target:  

Quinone Reductase

Research Areas:  

Metabolic Disease

NQO1 inducer 1 (Compound 20) is a potent NQO1 inducer (CD=3 μM). NQO1 inducer 1 is a promising antioxidant that can be used for the research of redox-modulating .
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Cat. No.: HY-N10445
Maydispenoid A is a potent immunosuppressor. Maydispenoid A can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .
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Cat. No.: HY-145288
CAS No.: 3005986-81-9
Target:  

Apoptosis

Research Areas:  

Cancer

Antitumor agent-36 possesses potent anti-proliferative and anti-metastasis activities. Antitumor agent-36 induces serious DNA damage and further leads to high expression of γ-H2AX and p53. Antitumor agent-36 promotes apoptosis of tumor cells through mitochondrial apoptotic pathway Bcl-2/Bax/caspase3. Antitumor agent-36 significantly improves immune response through restraining the expression of PD-L1 to increase CD3+ and CD8+ T infiltrating cells in tumor tissues .
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Cat. No.: HY-145289
CAS No.: 3032101-64-4
Target:  

Apoptosis

Research Areas:  

Cancer

Antitumor agent-37 possesses potent anti-proliferative and anti-metastasis activities. Antitumor agent-37 induces serious DNA damage and further leads to high expression of γ-H2AX and p53. Antitumor agent-37 promotes apoptosis of tumor cells through mitochondrial apoptotic pathway Bcl-2/Bax/caspase3. Antitumor agent-37 significantly improves immune response through restraining the expression of PD-L1 to increase CD3+ and CD8+ T infiltrating cells in tumor tissues .
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Cat. No.: HY-169480
CAS No.: 3003022-09-8
Target:  

Liposome

Research Areas:  

Infection Cancer

Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
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Cat. No.: HY-N10446
CAS No.: 3024647-69-3
Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .
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Cat. No.: HY-K0356

MCE Human CD3 Cell Depletion Magnetic Beads (Positive Selection) are magnetic beads covalently coupled with anti-human CD3 antibodies, enabling the specific binding and magnetic removal of CD3+ cells from single-cell suspensions derived from human peripheral blood mononuclear cells (PBMCs) or human peripheral blood leukocytes (WBCs). This allows efficient enrichment of the non-CD3+ cell population.

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Cat. No.: HY-RS17021
Research Areas:  

Others

Cd3e Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd3e gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P700678
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD3E; T3E; CD3 Epsilon Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; T-Cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Pol
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700677
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; T-Cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Prot
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77603
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; T-Cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Prot
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704103
Purity:  ≥ 90%, as determined by SDS-PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; T-Cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Prot
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704960
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; T-Cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Prot
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P77606
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD3E; T3E; CD3 Epsilon Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; T-Cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Pol
Species:  
Cynomolgus
Source:  
HEK293
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