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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
biosensor
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "biosensor" in MCE Product Catalog:
Cat. No.: HY-159945
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Tau Protein/α-synuclein-IN-2 (Compound 14T) is a blood-brain barrier penetrating tau and α-syn inhibitor. Through its thiourea linker structure, Tau Protein/α-synuclein-IN-2 dose-dependently reduces α-syn oligomerization. In biosensor cells, Tau Protein/α-synuclein-IN-2 prevents the seeding effect of tau aggregation. In the M17D neuroblastoma model, Tau Protein/α-synuclein-IN-2 exhibits anti-inclusion effects. Additionally, Tau Protein/α-synuclein-IN-2 reduces Aβ plaque formation. Tau Protein/α-synuclein-IN-2 holds promise for Alzheimer's disease and Parkinson's disease research.
Cat. No.: HY-W004570R
CAS No.: 4199-88-6
Synonyms: 5-NP (Standard)
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Cat. No.: HY-W1061408
CAS No.: 1263065-01-5
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Thiol-modifier C3 S-S Phosphoramidite is a thiol phosphoramidite modifier containing a C3 spacer and a disulfide linkage for introducing thiol functionality during oligonucleotide synthesis. Thiol-modifier C3 S-S Phosphoramidite can be used for reversible oligonucleotide conjugation, surface immobilization, and biosensor-related applications.
Cat. No.: HY-P11855
CAS No.: 557064-55-8
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Cat. No.: HY-D3445
CAS No.: 3029700-80-6
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JF629-HTL is a far-red fluorogenic HaloTag ligand. Binding of JF629-HTL to HaloTag protein alters the local environment of the dye, promoting the transition of rhodamine from a non-fluorescent state to a fluorescent state, thereby generating a fluorescence enhancement signal. In the light-controlled psHaloTag system, JF629-HTL shows a 6.7-fold fluorescence enhancement after irradiation at 450 nm. JF629-HTL serves as a research tool for far-red fluorescence imaging and the development of chemogenetic biosensors .
Cat. No.: HY-183657
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GPR3 inverse agonist-1 is a GPR3 inverse agonist with low micromolar potency in conformational analysis. GPR3 inverse agonist-1 inhibits GPR3-dependent Gs activity in HEK293A cells with an EC50 of 250 nM, and exhibits an EC50 of 2 μM in cAMP assays. GPR3 inverse agonist-1 induces concentration-dependent changes in BRET signals in GPR3 conformational biosensors (EC50 = 5 μM), reduces basal Gs activity downstream of GPR3, and competes for binding sites with the GPR3 agonist DPI (HY-100965). GPR3 inverse agonist-1 can be used in research related to Alzheimer's disease .
Cat. No.: HY-183657A
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GPR3 inverse agonist-1 TFA is a GPR3 inverse agonist with low micromolar potency in conformational analysis. GPR3 inverse agonist-1 TFA inhibits GPR3-dependent Gs activity in HEK293A cells with an EC50 of 250 nM, and exhibits an EC50 of 2 μM in cAMP assays. GPR3 inverse agonist-1 TFA induces concentration-dependent BRET signal changes in GPR3 conformational biosensors (EC50 = 5 μM), reduces basal Gs activity downstream of GPR3, competes for binding sites with the GPR3 agonist DPI (HY-100965). GPR3 inverse agonist-1 TFA can be used in research related to Alzheimer's disease .
Cat. No.: HY-185721
CAS No.: 25191-14-4
Synonyms: Polyguanylic acid
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Poly (G) (Polyguanylic acid) is a high-molecular-weight synthetic ribopolynucleotide. In the presence of Na + or K + ions, Poly (G) undergoes time-dependent structural modification, gradually self-assembling from a single strand into large G-quadruplex aggregates. Poly (G) undergoes cooperative secondary structure dissociation under alkaline conditions, but its secondary structure can withstand high temperatures up to 100°C and is resistant to snake venom diesterase at low Na + concentrations. Poly (G) forms stable 1:1 complexes with polycytidylic acid or poly 5-bromocytidylic acid, but does not bind to polyinosinic acid or polyadenylic acid. Poly (G) can be applied to studies on the interactions between drugs and G-rich DNA fragments in electrochemical biosensors .
Cat. No.: HY-W166106
CAS No.: 144631-82-3
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Bromoriluzole is a derivative of Riluzole (HY-B0211). Bromoriluzole inhibits Ca 2+ -dependent Calmodulin-SK4 channel interaction. Bromoriluzole is used for the research of neurodegenerative diseases .
Cat. No.: HY-D3435
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Biotin-X-DHPE is a biotin-labeled phospholipid analog that can be used for semi-automated cell panning in antibody discovery. Biotin-X-DHPE enables stable immobilization of live cells on magnetic beads without damaging the cells or altering their surface protein expression levels, while ensuring that the selected antibodies recognize natural, functional epitopes on the cell surface .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
