146 Results for "

circulation

" in MedChemExpress (MCE) Product Catalog:
Products (146)

146 Results for "circulation" in MCE Product Catalog:

Cat. No.: HY-127125
CAS No.: 15307-77-4
Purity:  99.28%
Target:  

COX

Research Areas:  

Inflammation/Immunology

Diclofenac ethyl ester is the prodrug of Diclofenac (HY-15036), that is encapsulated in polymer micelles in vitro, and released with prolonged circulation time and reduced drug concentrations in the heart and kidneys in vivo .
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Cat. No.: HY-U00172
CAS No.: 83656-38-6
Synonyms: C80-1324
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

Ipramidil (C80-1324) is a vasodilator with significant active dilation of coronary circulation in isolated hearts. Ipramidil can cause an increase in NO release and stimulate guanylate cyclase activity.
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Cat. No.: HY-N0298S
CAS No.: 515835-70-8
Stachydrine-d6 is a deuterated labeled Stachydrine (HY-N0298). Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway .
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Cat. No.: HY-137446
CAS No.: 2231749-54-3
Synonyms: BAY 1237592
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

Mosliciguat (BAY 1237592) is an apo-soluble guanylate cyclase activator. Mosliciguat improves cardiopulmonary circulation, reduces pulmonary arterial pressure in animal models, and its efficacy is enhanced under oxidative stress conditions. Mosliciguat exerts a bronchodilatory effect in a rat model of acetylcholine-induced bronchoconstriction. Mosliciguat can be used for research on pulmonary arterial hypertension .
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Cat. No.: HY-128891
CAS No.: 64840-90-0
Target:  

P2X Receptor

Research Areas:  

Neurological Disease

Eperisone ((±)-Eperisone) is an antispasmodic agent and centrally acting muscle relaxant useful in the study of diseases characterized by muscle stiffness and pain. Eperisone acts by relaxing skeletal and vascular smooth muscle, resulting in vasodilation, decreased muscle tone, improved circulation, and inhibition of pain reflexes. Eperisone is also a potent P2X7 receptor antagonist .
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Cat. No.: HY-176248
CAS No.: 14394-26-4
Dimephosphon is an anti-inflammatory agent with antihistamine and antiserotonin activities. Dimephosphon helps maintain the conduction function of the spinal cord and reduces the excitability of spinal motor neurons in the area surrounding the lesion. Dimephosphon directly activates lymphatic vessel movement and improves lymphatic circulation. Dimephosphon can be used for the study of inflammatory edema, acute spinal cord injury and lymphatic circulation disorders .
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Cat. No.: HY-N0298R
CAS No.: 471-87-4
Stachydrine (Standard) is the analytical standard of Stachydrine. This product is intended for research and analytical applications. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.
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Cat. No.: HY-124265S1
4β-Hydroxycholesterol-d5 is the deuterium labeled 4β-Hydroxycholesterol (HY-124265). 4β-Hydroxycholesterol is a major Cholesterol (HY-N0322) metabolite and a precursor in the synthesis of bile acids that is found in human circulation .
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Cat. No.: HY-106983
CAS No.: 192057-17-3
Research Areas:  

Inflammation/Immunology

GR 250495X is an inhaled glucocorticoid receptor agonist. GR 250495X is designed as a antedrug, which takes effect locally in the lungs but is rapidly metabolized and inactivated in the bloodstream after entering the systemic circulation, thereby minimizing systemic side effects. GR 250495X can be used in asthma research .
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Cat. No.: HY-Y1787R
CAS No.: 108-59-8
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .
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Cat. No.: HY-124265R
CAS No.: 17320-10-4
4β-hydroxy Cholesterol (Standard) is the analytical reference standard of 4β-hydroxy Cholesterol (HY-124265). This product is used for research and analytical applications. 4β-Hydroxycholesterol is a major Cholesterol (HY-N0322) metabolite and a precursor in the synthesis of bile acids that is found in human circulation .
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Cat. No.: HY-113958
CAS No.: 104653-34-1
Synonyms: LM-2219
Target:  

VD/VDR

Research Areas:  

Others

Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .
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Cat. No.: HY-113958R
CAS No.: 104653-34-1
Synonyms: LM-2219 (Standard)
Research Areas:  

Others

Difethialone (Standard) is the analytical standard of Difethialone. This product is intended for research and analytical applications. Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .
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Cat. No.: HY-163683
CAS No.: 2375590-67-1
Research Areas:  

Cancer

EB-PSMA-617 is a modified form of PSMA-617 that has enhanced pharmacokinetic properties by conjugating it to Evans Blue (EB) to extend its circulation half-life to improve prostate tumor uptake and radiotherapy efficacy. In preclinical studies using PC3-PIP-loaded mice, EB-PSMA-617 demonstrated prolonged blood half-life, increased accumulation in PSMA-positive tumors, and successful tumor elimination with lower radioactivity .
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Cat. No.: HY-173381A
Synonyms: Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .
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Cat. No.: HY-108011R
CAS No.: 15687-37-3
Naftazone (Standard) is the analytical standard of Naftazone. This product is intended for research and analytical applications. Naftazone is a naphthoquinone derivative, it can be used for the research of venous insufciency. Naftazone protects blood vessels, increases venous tonicity and capillary resistance, and improves lymphatic and venous circulation .
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Cat. No.: HY-B0233R
CAS No.: 75695-93-1
Synonyms: PN 200-110 (Standard)
Isradipine (Standard) is the analytical standard of Isradipine. This product is intended for research and analytical applications. Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease .
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Cat. No.: HY-B0233S2
CAS No.: 2747915-77-9
Synonyms: PN 200-110-d7
Isradipine-d7 is deuterated labeled Isradipine (HY-B0233). Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease .
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Cat. No.: HY-P2625S
Research Areas:  

Metabolic Disease

GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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Cat. No.: HY-P2625S1
Research Areas:  

Metabolic Disease

GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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