2231749-54-3
Chemical Structure
Mosliciguat
Synonym(s): BAY 1237592
- CAS No.: 2231749-54-3
- Formula:C41H36ClF3N2O5
- Molecular Weight:729.18
IUPAC Name: (S)-5-((4-carboxyphenethyl)(2-((3-chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)methoxy)phenethyl)amino)-5,6,7,8-tetrahydroquinoline-2-carboxylic acid
InChIKey: HFCWZVGKWGOBKV-QNGWXLTQSA-N
SMILES: OC(C1=CC=C(C2=N1)[C@H](CCC2)N(CCC(C=C3)=CC=C3C(O)=O)CCC(C=CC=C4)=C4OCC(C=CC(C(C=C5)=CC=C5C(F)(F)F)=C6)=C6Cl)=O
Biological Activity: Mosliciguat (BAY 1237592) is an apo-soluble guanylate cyclase activator. Mosliciguat improves cardiopulmonary circulation, reduces pulmonary arterial pressure in animal models, and its efficacy is enhanced under oxidative stress conditions. Mosliciguat exerts a bronchodilatory effect in a rat model of acetylcholine-induced bronchoconstriction. Mosliciguat can be used for research on pulmonary arterial hypertension[1].
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Mosliciguat | Mosliciguat (BAY 1237592) is an apo-soluble guanylate cyclase activator. Mosliciguat improves cardiopulmonary circulation, reduces pulmonary arterial pressure in animal models, and its efficacy is enhanced under oxidative stress conditions. Mosliciguat exerts a bronchodilatory effect in a rat model of acetylcholine-induced bronchoconstriction. Mosliciguat can be used for research on pulmonary arterial hypertension. | |||||||||||||||||||||
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Keywords
