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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10065 Results for "
functional
" in MedChemExpress (MCE) Product Catalog:
Products (10065)
10065 Results for "functional" in MCE Product Catalog:
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Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro.
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Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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2 Cited Publications
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S-Gboxin is a functional analog of the oxidative phosphorylation (OXPHOS) inhibitor Gboxin and has antitumor activity. S-Gboxin inhibits the growth of mouse and human glioblastoma with an IC50 of 470 nM. S-Gboxin has antitumor activity .
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2 Cited Publications
Cat. No.: HY-112612A
Purity: 98.06%
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RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist, with an EC50 of 25 nM in GPR88 cAMP functional assay. RTI-13951-33 hydrochloride reduces alcohol reinforcement and intake behaviors in rats .
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Exaluren (ELX-02; NB-124) is an synthetic eukaryotic ribosome-selective glycoside that induces read-through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren is used for the research of cystic fibrosis caused by nonsense mutations .
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2 Cited Publications
Synonyms: ELX-02 disulfate; NB-124 disulfate
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Exaluren (ELX-02; NB-124) disulfate is an synthetic eukaryotic ribosome-selective glycoside that induces read-through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren disulfate is used for the research of cystic fibrosis caused by nonsense mutations .
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2 Cited Publications
Cat. No.: HY-B0025
CAS No.: 83480-29-9
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2 Cited Publications
Cat. No.: HY-P1075
CAS No.: 261969-05-5
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2 Cited Publications
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UCK2 Inhibitor-1 (Compound 20874830-2) is a non-competitive UCK2 inhibitor with an IC50 of 4.7 μM. UCK2 Inhibitor-1 acts as a non-competitive inhibitor against uridine and ATP, and functionally inhibits the enzymatic activity of UCK2. UCK2 Inhibitor-1 suppresses the uridine salvage pathway. UCK2 Inhibitor-1 can be used in chronic myeloid leukemia research .
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2 Cited Publications
Cat. No.: HY-R00449A
hsa-miR-21-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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1 Cited Publications
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Methyltetrazine-amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates .
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1 Cited Publications
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Methyltetrazine-Amine hydrochloride is a tetrazine compound. Methyltetrazine-Amine hydrochloride can be used for the site-specific dual functionalization of the resulting bioconjugates. Methyltetrazine-Amine hydrochloride can be added during protein precipitation in experiments using trans-cyclooctene .
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1 Cited Publications
Cat. No.: HY-P7009
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: COL18A1; Collagen Alpha-1(XVIII) Chain Isoform 1 Preproprotein; Prev. KNO; Collagen, Type XVIII, Alpha 1, Isoform CRA_b; KNO1; Multi-functional Protein MFP; KS; Alternative Protein COL18A1; Collagen, Type XVIII, Alpha 1; Knobloch Syndrome, Type 1; Collage
Species:
Human
Source:
P. pastoris
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1 Cited Publications
Cat. No.: HY-P70347
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: COL18A1; Collagen Alpha-1(XVIII) Chain Isoform 1 Preproprotein; Prev. KNO; Collagen, Type XVIII, Alpha 1, Isoform CRA_b; KNO1; Multi-functional Protein MFP; KS; Alternative Protein COL18A1; Collagen, Type XVIII, Alpha 1; Knobloch Syndrome, Type 1; Collage
Species:
Mouse
Source:
HEK293
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1 Cited Publications
Cat. No.: HY-P5491
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1 Cited Publications
Synonyms: Deamido nad sodium
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1 Cited Publications
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Spermine(N3BBB) is a tri-Boc-protected azido-spermine reagent used for multi-functionalization of pseudo-glycodendrimers via click reaction .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
