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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
313 Results for "
antisense
" in MedChemExpress (MCE) Product Catalog:
Products (313)
313 Results for "antisense" in MCE Product Catalog:
Cat. No.: HY-134005
CAS No.: 1223657-78-0
Synonyms: FXI-ASO; BAY2306001; IONIS-FXIRx
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ISIS 416858, a single-stranded antisense oligodeoxynucleotide, is a potent and selective inhibitor of FXI mRNA expression.
Cat. No.: HY-132583A
Synonyms: DYM101 sodium
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IONIS-DNM2-2.5Rx sodium is an antisense agent targeting dynamin 2, and has the potential for the research of centronuclear myopathy (CNM) .
Cat. No.: HY-151123
CAS No.: 1637637-70-7
Synonyms: AKCEA-APO(a)-LRx; ISIS 681257; TQJ230
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Pelacarsen (ISIS 681257) is a GalNAc3-conjugated 2′-MOE-modified antisense oligonucleotide. Pelacarsen reduces apo (a) .
Cat. No.: HY-W190913
CAS No.: 2226472-28-0
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DBCO-PEG4-Val-Cit-PAB-PNP is a linker. DBCO-PEG4-Val-Cit-PAB-PNP conjugates anti-SYT2 monoclonal antibody with MALAT1 gapmer antisense oligonucleotides without inhibiting ASO activity or impairing the binding efficiency of the antibody to SYT2 antigen .
Cat. No.: HY-153495
CAS No.: 202484-91-1
Synonyms: BP1001
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Prexigebersen (BP1001) is an antisense oligonucleotide targeting Bcl-2 and Grb2. Prexigebersen exhibits antileukemic activity in cell models. Prexigebersen induces apoptosis (apoptosis), cell cycle arrest and ROS production in leukemia cells. Prexigebersen inhibits Grb2 expression, thereby suppressing tumor growth and survival. Prexigebersen can be used in studies related to acute myeloid leukemia .
Cat. No.: HY-149906C
Purity: 98.83%
Synonyms: GEM91 sodium
Trecovirsen sodium is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.
Cat. No.: HY-164419A
CAS No.: 1826859-79-3
Synonyms: COR-004 sodium; ATL1103 sodium; ISIS 227452 sodium
Atesidorsen sodium is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA
Cat. No.: HY-177653A
CAS No.: 2639854-33-2
Synonyms: AZD2373 sodium, ION-972190 sodium
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Opemalirsen sodium is an antisense oligonucleotide targeted to apolipoprotein L1 (APOL1). It is used for the study of Kidney disorders.
Cat. No.: HY-153495A
Purity: 95.60%
Synonyms: BP1001 sodium
Prexigebersen sodium is an antisense oligonucleotide designed to inhibit protein synthesis of Grb2 (growth factor receptor bound protein 2).
Cat. No.: HY-132593
CAS No.: 2072901-32-5
Synonyms: WVE-120101
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Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen can be used for huntington’s disease research .
Cat. No.: HY-159695A
Synonyms: ISIS 426115 sodium
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IONIS-GCCRRx (ISIS 426115) sodium, a glucocorticoid receptor antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO) .
Cat. No.: HY-148410C
Purity: 99.28%
Synonyms: STK-001 negative control
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Zorevunensen (STK-001) negative control is the negative control form of Zorevunensen (HY-148410). Zorevunensen is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome .
Cat. No.: HY-143230
CAS No.: 890056-27-6
Synonyms: OGX-011
Custirsen (OGX-011) is an antisense oligonucleotide that targets clusterin mRNA. Custirsen induces apoptosis by activating Bax, triggering mitochondrial translocation and cytochrome c release. Custirsen acts as a chemosensitizer, radiosensitizer and hormone sensitizer. Custirsen can be used in research related to prostate cancer, non-small cell lung cancer and metastatic breast cancer .
Cat. No.: HY-143230A
Purity: 98.71%
Synonyms: OGX-011 sodium
Custirsen sodium is a highly specific antisense oligonucleotide that inhibits the production of clusterin , an antiapoptotic protein that is upregulated in response to chemotherapy and that confers treatment resistance.
Cat. No.: HY-177651
CAS No.: 2834724-31-9
Synonyms: ION-582
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Obudanersen is an antisense oligonucleotide targeted to ubiquitin protein ligase E3A-antisense transcript (UBE3A-ATS). It is used for the study of Angelman syndrome.
0 Images
DNA, d([2′-O-(2-methoxyethyl)]rA-sp-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rC-A-sp-T-sp-T-sp-G-sp-G-sp-T-sp-G-sp-m5C-sp-A-sp-m5C-sp-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate], sodium salt (1:20)
Synonyms: ION-957943; BAY-2976217; IONIS-FXI-LRx sodium
Cat. No.: HY-177647
CAS No.: 2411937-33-0
Synonyms: BIIB-101; ION-464
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Movronersen is an antisense oligonucleotide targeted to α-synuclein.
Cat. No.: HY-177615A
Synonyms: GTX-102 sodium
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Apazunersen sodium is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient
Cat. No.: HY-177615
CAS No.: 2919324-01-7
Synonyms: GTX-102
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Apazunersen is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient protei
Cat. No.: HY-177649
CAS No.: 3053113-45-1
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Nivudirsen is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
