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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
134 Results for "
imaging detection
" in MedChemExpress (MCE) Product Catalog:
Products (134)
134 Results for "imaging detection" in MCE Product Catalog:
Cat. No.: HY-173384
Synonyms: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
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DSPE-DOTA sodium (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt) is a chelating lipid used as a key contrast agent in magnetic resonance imaging (MRI). DSPE-DOTA sodium can be used for imaging detection of tumors, neurological and inflammatory diseases .
Cat. No.: HY-136201R
CAS No.: 31138-65-5
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Sodium Glucoheptonate (Standard) is the analytical standard of Sodium Glucoheptonate. This product is intended for research and analytical applications. Sodium Glucoheptonate is used as a kit for radio-labeling with Tc-99m. Tc-99m glucoheptonate is kidney- and brain-imaging agent, and can be used in brain-tumor detection[1][2].
Cat. No.: HY-152103
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CB2-H is a dual-channel fluorescent probe for the simultaneous detection of HOCl and ONOO -. CB2-H enables the concurrent detection of HOCl and ONOO - at two independent channels without spectral cross-interference and can be applied for dual-channel fluorescence imaging of endogenously produced HOCl and ONOO - in living cells and zebrafish under different stimulants .
Cat. No.: HY-155438
CAS No.: 2883232-96-8
Cat. No.: HY-D2843
Cat. No.: HY-W066890R
CAS No.: 3316-09-4
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Cat. No.: HY-P5228A
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Cat. No.: HY-172754
Cat. No.: HY-D3075
CAS No.: 2490504-23-7
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TPE-2E N-oxide is a fluorescent probe used for hypoxia detection and tumor hypoxia imaging. Due to its active intramolecular motion, TPE-2E N-oxide shows no fluorescence in aqueous solution. In hypoxic environments, its N-oxide group undergoes two-electron reduction by CYP450 reductase and other heme protein reductases expressed under hypoxia, forming hydrophobic aggregates that trigger aggregation-induced emission through the restriction of intramolecular motion. TPE-2E N-oxide exhibits selective lipid droplet localization in cells. The absorption wavelength of TPE-2E N-oxide in dichloromethane is 313 nm; in a 99% hexane/dichloromethane mixed system, its excitation wavelength is 330 nm and emission wavelength is 460 nm. For in vitro cell imaging, excitation is performed at 405 nm, with an emission wavelength range of 430-560 nm .
Cat. No.: HY-D3157
CAS No.: 2133002-04-5
Cat. No.: HY-D3125
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NtHzBtd is a fluorescent probe for detecting Fe 3+. NtHzBtd is applicable to the selective fluorescent detection of Fe 3+ ions and live cell imaging studies. NtHzBtd can selectively coordinate with Fe 3+ to form a 1:1 complex, triggering chelation enhanced quenching (CHEQ) and intramolecular charge transfer (ICT) processes, which result in fluorescence turn-off, thereby enabling sensitive detection of Fe 3+ and live cell fluorescence imaging. After binding to Fe 3+, NtHzBtd reduces fluorescence intensity, exhibits a rapid response property, with a limit of detection of 0.036 μM and a response time of approximately 55 s. The detection wavelengths are Ex/Em = 334/401 nm (solution system) .
Cat. No.: HY-D3365
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RL560 is a red-emitting RNA fluorescent dye used for RNA-selective labeling and live-cell RNA imaging. RL560 achieves RNA-selective fluorescence turn-on via covalent acylation between its acylimidazole reactive group and the 2′-OH of RNA ribose, as well as fluorescence signal enhancement through restriction of TICT molecular motion. RL560 is applicable for RNA imaging and multicolor RNA detection, with detection wavelengths of Ex/Em = 560/639 nm .
Cat. No.: HY-D3132
CAS No.: 1616505-01-1
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Spring Red is a fluorescent probe for mitochondrial pH detection (Ex/Em = 530/680 nm) that can be taken up by live cells and mitochondria. The detection mechanism of Spring Red depends on pH changes and mitochondrial membrane potential. Fluorescence intensity increases with elevated pH, and a significant pH-dependent fluorescent response is observed in the pH range of 5.0‑8.0. Spring Red is suitable for long-term live-cell imaging and in vivo imaging, and can be used to monitor dynamic mitochondrial pH changes .
Cat. No.: HY-D3083
CAS No.: 2894792-95-9
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MOM is a polarity-sensitive fluorescent probe that can be used for cancer cell membrane, tumor imaging and cell membrane polarity detection (Ex/Em=488/570−630 nm). MOM can also be applied for in vivo imaging, with an Ex/Em of 460/600 nm in living animals, and exhibits photostability .
Cat. No.: HY-D3096
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TPh-PyBz-β-gal is a fluorescent probe used for the detection and imaging of β-galactosidase (β-gal) in living cells. The detection mechanism of TPh-PyBz-β-gal relies on β-gal, which cleaves the glycosidic bond linking the AIE-active fluorophore and the D-galactose residue unit of the probe. The emission wavelength of TPh-PyBz-β-gal after activation is 606 nm. TPh-PyBz-β-gal has low cytotoxicity and can be applied to β-gal imaging in living cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
