172 Results for "

simplex

" in MedChemExpress (MCE) Product Catalog:
Products (172)

172 Results for "simplex" in MCE Product Catalog:

Cat. No.: HY-P5644
CAS No.: 724760-21-8
Target:  

Bacterial

Research Areas:  

Infection

Retrocyclin-3 is an antimicrobial peptide against human immunodeficiency virus, influenza A and herpes simplex virus .
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Cat. No.: HY-N6666R
CAS No.: 24356-66-9
Vidarabine monohydrate (Standard) is the analytical standard of Vidarabine monohydrate (HY-N6666). This product is intended for research and analytical applications. Vidarabine monohydrate is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine monohydrate competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine monohydrate inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine monohydrate is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine monohydrate can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
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Cat. No.: HY-130564
CAS No.: 77327-06-1
Target:  

HSV

Research Areas:  

Infection Cancer

Didemnin C is a cyclic depsipeptide. Didemnin C inhibits the proliferation of herpes simplex virus (HSV) and exhibits activity against both RNA viruses and DNA viruses. Didemnin C is cytotoxic to cancer cells. Didemnin C can be used in studies related to herpes simplex virus type 2 infection and cancer .
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Cat. No.: HY-163546
CAS No.: 3044784-31-5
Target:  

HSV

Research Areas:  

Infection

HSV-1-IN-1 (compound 1b) is a drug candidate for herpes simplex virus HSV-1(IC50=0.5 nM) and HSV-2(IC50=16 nM) infection. HSV-1-IN-1 inhibits the helicase-primase complex to prevent viral replication, thereby inhibiting HSV infection .
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Cat. No.: HY-121763
CAS No.: 112446-99-8
Target:  

HSV

Research Areas:  

Infection

SCH-43478 is a non-nucleoside antiviral agent. SCH-43478 shows potent and selective activity against herpes simplex virus type 2 (HSV-2) with an IC50 of 1.8 μg/mL using Vero cells. SCH-43478 demonstrates significant efficacy in the guinea pig genital model of HSV infection .
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Cat. No.: HY-176163
Target:  

HSV

Research Areas:  

Infection

HSV-1-IN-2 (compound 5i) is a potent Herpes simplex virus type 1 (HSV-1) inhibitor with an EC50 of 1.95 μM. HSV-1-IN-2 inhibits apoptosis and improves herpes encephalitis model mouse survival .
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Cat. No.: HY-B0420AR
CAS No.: 3160-91-6
Synonyms: ABOB hydrochloride (Standard)
Moroxydine (ABOB) hydrochloride (Standard) is the analytical standard of Moroxydine (ABOB) hydrochloride (HY-B0420A). Moroxydine (ABOB) hydrochloride is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine hydrochloride blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine hydrochloride significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels.
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Cat. No.: HY-126476
CAS No.: 79162-16-6
Justicisaponin I can be used as an anti-fertility agent. Justicisaponin I stabilizes the acrosome membrane of sperm, and inhibits the release of acid hydrolase and sperm proteins .
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Cat. No.: HY-N14563
CAS No.: 142382-45-4
Cycloviracin B1 has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-Gram-positive bacterial activity .
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Cat. No.: HY-15303S
Synonyms: AIC316-d4-1; BAY 57-1293-d4-1
Pritelivir-d4-1 (AIC316-d4-1) is deuterium labeled Pritelivir. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
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Cat. No.: HY-N14564
CAS No.: 142382-46-5
Cycloviracin B2 is an antibiotic with antiviral activity. Cycloviracin B2 has a strong inhibitory activity against herpes simplex virus type 1 (HSV-1) .
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Cat. No.: HY-N14265
CAS No.: 155683-51-5
Kistamicin B has antiviral effect, and its ID50s against influenza virus MDCK cells and herpes simplex virus are respectively 1.8 μg/mL and 30 μg/mL .
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Cat. No.: HY-P4318
CAS No.: 2022956-63-2
Target:  

HSV

Research Areas:  

Infection

HHV-2 Envelope Glycoprotein G (552-574) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .
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Cat. No.: HY-145246
Biotin-PEG8-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses .
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Cat. No.: HY-N12191
CAS No.: 155944-24-4
Cangorinine E-1 (compound 11) is a dihydroagarofuran derivative of the sesquiterpenoid family. Cangorinine E-1 exhibits weak inhibitory effects on herpes simplex virus type II (HSV) .
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Cat. No.: HY-177638A
Target:  

HSV

Research Areas:  

Infection

ISIS 1082 sodium is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
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Cat. No.: HY-W705873
Synonyms: EUDR-d5
Edoxudine-d5 (EUDR-d5) is the deuterium labeled Edoxudine (HY-B1011). Edoxudine is an antiviral active molecule and thymidine analog. Edoxudine is effective against herpes simplex virus .
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Cat. No.: HY-145247
Biotin-PEG7-C2-S-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses .
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Cat. No.: HY-N14446
CAS No.: 175413-72-6
Target:  

HSV

Karalicin inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC50s (μg/mL) of 0.004, 0.008, 0.016 and 0.016 .
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Cat. No.: HY-N14264
CAS No.: 155683-50-4
Kistamicin A has antiviral effect, and its ID50s against influenza virus MDCK cells and herpes simplex virus are respectively 3.6 μg/mL and 44 μg/mL. Kistamicin A also has anti-Gram-positive bacterial effects .
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