113 Results for "

RGD

" in MedChemExpress (MCE) Product Catalog:
Products (113)

113 Results for "RGD" in MCE Product Catalog:

Cat. No.: HY-W782087A
CAS No.: 2649490-34-4
p-SCN-Bn-PCTA hydrochloride is a Bifunctional Chelator used for radiometal labeling. p-SCN-Bn-PCTA hydrochloride can conjugate with peptides or antibodies via its isothiocyanate group. PCTA-RGD, formed by the conjugation of p-SCN-Bn-PCTA with cyclo-RGDyK, retains binding activity towards αvβ3 integrin with an IC50 of 1.8 μM. p-SCN-Bn-PCTA hydrochloride can be used for the construction of PET radiotracers and imaging studies related to pancreatic cancer, colorectal cancer, and tumor angiogenesis .
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Cat. No.: HY-P3448S
Synonyms: CEND-1-13C6,15N2; iRGD-13C6,15N2; LSTA1-13C6,15N2
Certepetide- 13C6, 15N2 (CEND-1- 13C6, 15N2) is the 13C- and 15N-labeled Certepetide (HY-P3448). Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors .
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Cat. No.: HY-P2635
CAS No.: 91575-25-6
Target:  

Integrin

Research Areas:  

Cancer

RGDSPASSKP is a RGDS-containing fibronectin decapeptide .
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Cat. No.: HY-P11384
CAS No.: 144161-76-2
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

D-RGDW is an Arg-Gly-Asp (RGD) containing peptide. D-RGDW inhibits αIIbβ3 mediated platelet aggregation .
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Cat. No.: HY-P1702
CAS No.: 152323-73-4
Target:  

Integrin

Research Areas:  

Others

GR83895 is a RGD based peptide, and inhibits ADP-induced platelet aggregation of human gel-filtered platelets (IC50= 0.9 μM) .
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Cat. No.: HY-P3530
CAS No.: 111844-21-4
Target:  

Integrin

Research Areas:  

Others

G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption .
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Cat. No.: HY-P0322A
Synonyms: EMD 56574 TFA
Target:  

Integrin

GRGDSPK TFA (EMD 56574 TFA) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK TFA is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK TFA is used to study the role of integrins in bone formation and resorption .
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Cat. No.: HY-157157
CAS No.: 2642327-44-2
Research Areas:  

Cancer

PAD4-IN-3 (compound 4B) is a PAD4 inhibitor with antitumor activity in vitro and in vivo. PAD4-IN-3 was covalently linked to RGD sequence peptide-modified chitosan (K-CRGDV), resulting in an enhanced oxidative stress-responsive nanoagent. K-CRGDV-PAD4-IN-3 can actively target tumors, inhibit PAD4 activity, block the formation of neutrophil extracellular traps (NETs), and improve the tumor immune microenvironment in response to the tumor microenvironment .
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Cat. No.: HY-126039
CAS No.: 168157-33-3
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

L-739758 is an antagonist for αIIbβ3 integrin (platelet glycoprotein IIb/IIIa). L-739758 acts as a peptidomimetic, binds to αIIbβ3 integrin by mimicking the interaction of the RGD (arginine-glycine-aspartic acid) motif, and is involved in the blood coagulation process. L-739758 inhibits platelet aggregation, and is used for thrombosis research .
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Cat. No.: HY-167686
CAS No.: 3187-52-8
Synonyms: Homopisatin
Variabilin (Homopisatin) is a potent RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis. Variabilin potently inhibits platelet aggregation induced by the platelet agonists ADP, collagen, and thrombin receptor peptide SFLLRNP. Variabilin also blocks platelet adhesion to immobilized Fg. In addition, Variabilin inhibits binding of purified human GPIIb-IIIa to immobilized Fg .
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Cat. No.: HY-126402
CAS No.: 120103-89-1
Target:  

Integrin

Research Areas:  

Cancer

Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1. It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.
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Cat. No.: HY-P3448S1
Synonyms: CEND-1-13C2,15N; iRGD-13C2,15N; LSTA1-13C2,15N
Certepetide- 13C2, 15N (CEND-1- 13C2, 15N) is the 13C- and 15N-labeled Certepetide (HY-P3448). Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors .
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Cat. No.: HY-168943A
PLGA nanoparticles, 200nm, are biodegradable tumor-targeting nanocarriers that can serve as drug delivery enhancers and multidrug resistance inhibitors. PLGA nanoparticles, 200nm, passively enriched through the EPR effect and actively targeted via ligand-mediated endocytosis, can encapsulate various antitumor active molecules. PLGA nanoparticles, 200nm can specifically recognize multiple types of tumor cells and improve cellular uptake, cytotoxicity and antiproliferative effects after modification with ligands such as transferrin, folic acid, and RGD. PLGA nanoparticles, 200nm can encapsulate various therapeutic drugs and can be surface modified to achieve targeting, imaging, and prolonged circulation time, making them suitable for cancer-related research .
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Cat. No.: HY-168943B
PLGA nanoparticles, 500nm, are biodegradable tumor-targeting nanocarriers that can serve as drug delivery enhancers and multidrug resistance inhibitors. PLGA nanoparticles, 500nm, passively enriched through the EPR effect and actively targeted via ligand-mediated endocytosis, can encapsulate various antitumor active molecules. PLGA nanoparticles, 500nm can specifically recognize multiple types of tumor cells and improve cellular uptake, cytotoxicity and antiproliferative effects after modification with ligands such as transferrin, folic acid, and RGD. PLGA nanoparticles, 500nm can encapsulate various therapeutic drugs and can be surface modified to achieve targeting, imaging, and prolonged circulation time, making them suitable for cancer-related research .
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Cat. No.: HY-168943C
PLGA nanoparticles, 1μm, are biodegradable tumor-targeting nanocarriers that can serve as drug delivery enhancers and multidrug resistance inhibitors. PLGA nanoparticles, 1μm, passively enriched through the EPR effect and actively targeted via ligand-mediated endocytosis, can encapsulate various antitumor active molecules. PLGA nanoparticles, 1μm can specifically recognize multiple types of tumor cells and improve cellular uptake, cytotoxicity and antiproliferative effects after modification with ligands such as transferrin, folic acid, and RGD. PLGA nanoparticles, 1μm can encapsulate various therapeutic drugs and can be surface modified to achieve targeting, imaging, and prolonged circulation time, making them suitable for cancer-related research .
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Cat. No.: HY-P11773
CAS No.: 1094848-94-8
Research Areas:  

Others

3P-RGD2 is a dimeric cyclic RGD (Arg-Gly-Asp) peptide. When radiolabeled with 99mTc, 3P-RGD2 serves as a selective radiotracer for integrin αvβ3. When radiolabeled with 99mTc, 3P-RGD2 enables single-photon emission computed tomography imaging of integrin αvβ3 .
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Cat. No.: HY-P11774
CAS No.: 1094848-99-3
Target:  

Integrin

Research Areas:  

Cancer

HYNIC-3P-RGD2 is a dimeric cyclic RGD peptide with high binding affinity for integrin αvβ3 (IC50 = 33 nM). HYNIC-3P-RGD2 acts as a precursor molecule for radiotracers and is used to detect tumor angiogenesis .
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Cat. No.: HY-P11416
CAS No.: 122207-62-9
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (Ki = 4.2 μM), inhibiting the binding of fibrinogen to platelets and thereby effectively suppressing platelet aggregation. Ac-RGDS-NH2 can be used for research on thrombosis .
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Cat. No.: HY-P82770
Synonyms: RGD1565941; VAV 3; Vav3; VAV3 oncogene

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-P74525
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TGFBI; RGD-Containing Collagen-Associated Protein; Prev. CSD1; Beta Ig-H3; Prev. CSD2; RGD-CAP; Prev. CSD3; Transforming Growth Factor, Beta-Induced, 68kDa; Prev. LCD1; Transforming Growth Factor Beta-Induced 68kDa; BIGH3; Transforming Growth Factor Beta
Species:  
Human
Source:  
HEK293
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