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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
109 Results for "
VC
" in MedChemExpress (MCE) Product Catalog:
Products (109)
109 Results for "VC" in MCE Product Catalog:
Cat. No.: HY-173625
CAS No.: 2928571-52-0
Research Areas:
P5(PEG12)-VC-PAB-Exatecan (LP3) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker P5(PEG24)-VC-PAB to make antibody agent conjugate (ADC). P5(PEG12)-VC-PAB-Exatecan can be used for the research of tumor .
SC-VC-PAB-N-Me-L-Ala-Maytansinol (compound B1) can be used to synthesis MCC-Maytansinoid A. SC-VC-PAB-N-Me-L-Ala-Maytansinol can be used as a control compound for the cancer research .
Cat. No.: HY-171684
Research Areas:
Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) consisting of the humanized anti-CCL2 (chemokine ligand 2) antibody Carlumab (HY-P99188) conjugated to the linker Mc-VC-PAB and the topoisomerase I inhibitor SN38 (HY-13704). The ADC toxic molecule and linker part are Mc-VC-PAB-SN38 (HY-131057). Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 can be used in cancer research .
Cat. No.: HY-157465A
Purity: 99.05%
Target:
Research Areas:
MA-PEG4-VC-PAB-DMEA-duocarmycin DM TFA is a drug-linker conjugate for ADC by using the DNA minor-groove alkylator Duocarmycin DM (HY-130978), linked via MA-PEG4-vc-PAB-DMEA (HY-126668).
Cat. No.: HY-171738
Research Areas:
Anti-SLC34A2 (Lifastuzumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) consisting of the humanized anti-SLC34A2 (sodium-dependent phosphate transporter 2) antibody Lifastuzumab (HY-P99970) conjugated to the linker Mc-VC-PAB and the topoisomerase I inhibitor SN38 (HY-13704). The ADC toxic molecule and linker part are Mc-VC-PAB-SN38 (HY-131057). Anti-SLC34A2 (Lifastuzumab)-MC-Vc-PAB-SN38 can be used in cancer research .
Cat. No.: HY-48668
CAS No.: 1609108-48-6
Target:
Research Areas:
AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate .
Cat. No.: HY-171685
Target:
Antibody-Drug Conjugates (ADCs) CCR DNA Alkylator/Crosslinker ADC Payloads Antibiotic Apoptosis
Research Areas:
Anti-CCL2 (Carlumab)-MC-Vc-PAB-DMEA-PEG2-Duocarmycin SA is an antibody-drug conjugate (ADC) consisting of the humanized anti-CCL2 (chemokine ligand 2) antibody Carlumab (HY-P99188) conjugated with the linker MC-Vc-PAB-DMEA-PEG2 and the DNA alkylator Duocarmycin SA (HY-12456). Anti-CCL2 (Carlumab)-MC-Vc-PAB-DMEA-PEG2-Duocarmycin SA can be used in cancer research .
Cat. No.: HY-126668A
Target:
Research Areas:
Mal-PEG4-VC-PAB-DMEA TFA is a degradable ADC linker containing a maleimide group and can be used to synthesize antibody conjugate active molecules (ADCs) .
Cat. No.: HY-126677
Target:
Research Areas:
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-171113
CAS No.: 3112948-10-1
Synonyms: VC-LC-1074
CP-LC-1143 is an ionizable cationic amino lipid efficient delivery of different kinds of RNA (mRNA, cRNA and saRNA).
Cat. No.: HY-162782A
Target:
Research Areas:
V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria .
Cat. No.: HY-157501
CAS No.: 2922217-01-2
Target:
Research Areas:
PC6-VC-PAB-MMAE is a Drug-Linker Conjugates for ADC. PC6-VC-PAB-MMAE consists of the ADC Cytotoxin MMAE (HY-15162) and a linker. PC6-VC-PAB-MMAE can be used for synthesis of ADCs .
Cat. No.: HY-185493
CAS No.: 1661823-95-5
Target:
Research Areas:
Mal-VC-PAB-seco-CBI-PBD dimer is a highly active drug-linker conjugate. Mal-VC-PAB-seco-CBI-PBD dimer integrates the DNA-damaging effects of two distinct types of compounds: seco-cyclopropabenzindoline (seco-CBI) and pyrrolobenzodiazepine (PBD). Mal-VC-PAB-seco-CBI-PBD dimer is linked via a valine-alanine (VC) linker cleavable by cathepsin B and achieves targeted delivery relying on monoclonal antibodies. Mal-VC-PAB-seco-CBI-PBD dimer is applicable for cancer research .
Cat. No.: HY-185845
Target:
Research Areas:
MC-VC-PAB-PEG4-DBCO is a protease-cleavable ADC linker composed of Mc-VC-PAB and PEG4-DBCO moieties .
Cat. No.: HY-185153
Target:
Research Areas:
MC-VC-PAB-DMEA-PEG2-Duocarmycin SA is a drug-linker conjugate for ADC. MC-VC-PAB-DMEA-PEG2-Duocarmycin SA can be coupled with Carlumab (HY-P99188) to form Anti-CCL2 (Carlumab)-MC-Vc-PAB-DMEA-PEG2-Duocarmycin SA (HY-171685).
Cat. No.: HY-185846
Target:
Research Areas:
Mal-VC-PAB-PEG4-DBCO is a cleavable ADC linker that can be used in the synthesis of ADCs.
Cat. No.: HY-185664
CAS No.: 3063856-91-4
Target:
Research Areas:
2-MSP-2-(pent-4-yn-1-yloxy)acetic acid-VC-PAB-Eribulin is a drug-linker conjugate comprising Eribulin (HY-13442), can be used for preparation of multi-projectile antibody-drug conjugates (ADCs).2-MSP-2-(pent-4-yn-1-yloxy)acetic acid-VC-PAB-Eribulin can be used for the research of tumor diseases .
Cat. No.: HY-106583R
CAS No.: 87234-24-0
Synonyms: Cinnoxicam (Standard); SPA-S-510 (Standard); Sinartol (Standard)
Target:
Research Areas:
Piroxicam cinnamate (Standard) is the analytical standard of Piroxicam cinnamate (HY-106583). This product is intended for research and analytical applications. Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor, with anti-inflammatory activity. Piroxicam cinnamate is stable under gastric conditions, can be used for inflammatory-degenerative osteoarticular diseases, rheumatic disorders, and varicocele (VC) associated oligoasthenospermia research .
Cat. No.: HY-172925
CAS No.: 3112948-20-3
Synonyms: VC-LC-1447
CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine.
Cat. No.: HY-W1130407
CAS No.: 3112948-09-8
Synonyms: VC-LC-1073
CP-LC-1073 is a specific ionizable cationic amino lipid derived from the amino acid homocysteine. CP-LC-1073 can used in lipid nanoparticle (LNP) formulations for efficient in vivo delivery and expression of RNA (mRNA, cRNA, saRNA).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
