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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
140 Results for "
Configuration
" in MedChemExpress (MCE) Product Catalog:
Products (140)
140 Results for "Configuration" in MCE Product Catalog:
Cat. No.: HY-148826A
Synonyms: ARC 183 sodium; BC 007 sodium
Target:
Domaines de recherche:
Rovunaptabin sodium (ARC 183 sodium) is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity and specificity.
Cat. No.: HY-183036
CAS No.: 3089179-09-6
Domaines de recherche:
ABC transporter modulator-5 (I-677-Isomer 2 (R configuration)) is a ABC modulator. ABC transporter modulator-5 is used in studies of ABC dysfunction .
Cat. No.: HY-138198
CAS No.: 214265-97-1
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Domaines de recherche:
(E)-YIC-C8-434 is the E double-bond configuration of YIC-C8-434. YIC-C8-434 is an orally active ACAT inhibitor with anti-hypercholesterolemic activity .
Cat. No.: HY-183035
CAS No.: 3089179-10-9
Domaines de recherche:
ABC transporter modulator-4 (I-677-Isomer 1 (S configuration)) is a ABC transporter expression modulator. ABC transporter modulator-4 is used in studies of ABC transporter dysfunction .
Cat. No.: HY-185234
CAS No.: 3068779-36-9
Target:
Domaines de recherche:
Cardiovascular Disease Neurological Disease Metabolic Disease
CTR/AMYR activator-1 (S configuration of compound 122) is a CTR/AMYR activator. CTR/AMYR activator-1 can be used in the research of bone diseases, metabolic diseases, cardiovascular diseases, and neurodegenerative diseases .
Cat. No.: HY-N21812B
Target:
Cat. No.: HY-W725194
CAS No.: 3048183-53-2
Synonyms: 4-FDCK hydrochloride
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Domaines de recherche:
4-Fluoro deschloroketamine (4-FDCK) hydrochloride (Page 145) is an amine cyclohexane compound, with its (R)-configuration being Blixeprodil (HY-172419) (an NMDA receptor antagonist). 4-Fluoro deschloroketamine hydrochloride can be used for the study of depression .
Cat. No.: HY-180192
CAS No.: 3106089-54-4
Dehydroxy-oridonin-vinyl ester (Compound 6k) is an anti-cancer agent. Dehydroxy-oridonin-vinyl ester exhibits extremely strong anti-proliferative activity against SU-DHL-6 cells, with its IC₅₀ value being 0.12 μM. Dehydroxy-oridonin-vinyl ester induces cell apoptosis by inhibiting the activation of the PI3K/Akt signaling pathway, without affecting the cell cycle progression. Dehydroxy-oridonin-vinyl can be used for the study of lymphoma .
Cat. No.: HY-N18105
CAS No.: 53938-05-9
Category:
Alkaloids Other Alkaloids Celastraceae Gymnosporia arbutifolia (Hochst. ex A.Rich.) Loes. Plants
Target:
Cat. No.: HY-137557A
Synonyms: (E/Z)-APN1607; (E/Z)-PM-PBB3
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Domaines de recherche:
(E/Z)-Florzolotau ((E/Z)-APN1607) is a mixed configuration or unspecified configuration of Florzolotau (HY-137557). Florzolotau (APN1607) is a positron emission tomography (PET) ligand that can be used for the detection of Alzheimer's disease (AD) and other tau proteinopathies. Its binding sites are located in the β-sheet of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein, as well as in the C-shaped cavity of SFs. In addition, APN-1607 binds to intraneuronal inclusions in Alzheimer's disease (AD), primary age-related tauopathy (PART) and posterior cortical atrophy (PCA). Florzolotau shows promise for PET imaging studies of neurological disorders, particularly tau proteinopathies .
Cat. No.: HY-N21537
CAS No.: 83156-03-0
Target:
Cat. No.: HY-N21539
Target:
Cat. No.: HY-N21548
CAS No.: 1425047-04-6
Target:
Cat. No.: HY-15322A
CAS No.: 1194954-52-3
Synonyms: (rel)-P505-15; (rel)-PRT-2607; (rel)-BIIB-057
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Domaines de recherche:
(rel)-PRT062607 ((rel)-P505-15) is the relative configuration of PRT062607 (HY-15322). PRT062607 is a highly selective inhibitor of Syk kinase, with an IC50 value of 1-2 nM, and is more than 80 times less potent against Fgr, Lyn, FAK, Pyk2, and Zap70.
Cat. No.: HY-163825A
CAS No.: 1217403-51-4
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Domaines de recherche:
(E)-RNB-61 is the E configuration of RNB-61 (HY-163825). RNB-61 is an orally active cannabinoid CB2 receptor (CB2R) agonist with a Ki range of 0.13 nM to 1.81 nM. RNB-61 has renal protective and/or anti-fibrotic effects .
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Domaines de recherche:
Phenindamine hydrochloride (Nu 1504 hydrochloride) is the hydrochloride salt of Phenindamine (HY-A0149). Phenindamine is a histamine H1 receptor antagonist. Phenindamine hydrochloride mainly exists in the 9-9a ene configuration and as a mixture of protonated epimers. Phenindamine hydrochloride can be used in studies related to histamine H1 receptor antagonists and the salt-type structure of Phenindamine .
Cat. No.: HY-148336
CAS No.: 2407753-09-5
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Domaines de recherche:
(E)-IDO1/TDO-IN-5 is the E configuration of IDO1/TDO-IN-5 (HY-148336A). IDO1/TDO-IN-5 is a dual IDO1/TDO inhibitor with IC50 values of 0.018 and 0.025 μM, respectively .
Cat. No.: HY-E71225
Target:
Domaines de recherche:
α-D-Xyloside xylohydrolase (EC 3.2.1.177) catalyses hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide. Representative α-xylosidases from glycoside hydrolase family 31 utilize a two-step (double-displacement) mechanism involving a covalent glycosyl-enzyme intermediate, and retain the anomeric configuration of the product.
Cat. No.: HY-108286A
CAS No.: 71369-59-0
Synonyms: (-)-Cordanum
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Domaines de recherche:
(-)-Talinolol ((-)-Cordanum) is the S-configuration levorotatory single optical enantiomer of the racemic mixture of Talinolol (HY-108286). Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol possesses cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used substrate for P-glycoprotein (P-gp) active probes.
Cat. No.: HY-186059A
CAS No.: 3080809-02-2
Target:
Domaines de recherche:
HCN2 modulator-5 (S-configuration 39) is a HCN2 ion channel inhibitor. HCN2 modulator-5 inhibits HCN2 ion channel activity. HCN2 modulator-5 can be used for the research of pain, inflammatory pain, neuropathic pain, tinnitus, central nervous system disorders, psychiatric disorders, mood disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
