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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
349 Results for "
activation system
" in MedChemExpress (MCE) Product Catalog:
Products (349)
349 Results for "activation system" in MCE Product Catalog:
Cat. No.: HY-W040055R
CAS No.: 2009-64-5
Synonyms: D-(+)-Neopterin (Standard); D-erythro-Neopterin (Standard)
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VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus .
Cat. No.: HY-P1298
CAS No.: 74434-59-6
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Sauvagine is a corticotropin-releasing factor receptor (CRFR) agonist. Sauvagine activates HM-CRF receptors to stimulate intracellular cAMP accumulation, activates PC-CRF receptors to trigger associated signaling pathways, and stimulates the hypothalamic-pituitary-adrenal axis. Sauvagine can be used for research on central nervous system and blood diseases .
Cat. No.: HY-16785B
CAS No.: 1093131-03-3
Synonyms: INXN-1001 (S enantiomer); RG-115932 (S enantiomer)
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Veledimex S enantiomer (INXN-1001 S enantiomer) is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system, and a moderate inhibitor of and substrate for CYP3A4/5 .
Cat. No.: HY-113313R
CAS No.: 52-39-1
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H2S Donor 5a is a cysteine-activated H2S donor. H2S plays important roles in biological systems. H2S Donor 5a is a useful tool in H2S research .
Cat. No.: HY-N10546A
CAS No.: 1007119-81-4
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Ganglioside GM1 (bovine) ammonium is a type of glycosphingolipid, mainly found on the cell membranes of the central nervous system of vertebrates. Ganglioside GM1 (bovine) ammonium exerts neuroprotective effects by reducing excessive activation of NMDAR, activating TrkA and ERK1/2, and inhibiting oxidative stress and cell apoptosis and autophagy. Ganglioside GM1 (bovine) ammonium can be used in the research of diseases such as traumatic brain injury, Parkinson's disease, Alzheimer's disease, and Huntington's disease .
Cat. No.: HY-148420
CAS No.: 2586047-09-6
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CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes .
Cat. No.: HY-160197
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Aluminum phosphate adjuvant is a safe and effective adjuvant that activates immune system and immune system-related pathways in monocytes .
Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min .
In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain . 2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .
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Propiolamide is a monooxygenase (MMO) system activator and glutathione peroxidase 4 (GPX4) inhibitor. Propiolamide induces ROS production through interaction with the MMO system. Propiolamide promotes the accumulation of intracellular cytotoxic lipid peroxides and induces ferroptosis. Propiolamide induces programmed cell death via the apoptosis pathway. Propiolamide can be used in cancer research .
Cat. No.: HY-174728
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Human CXCR1 mRNA encodes the human C-X-C motif chemokine receptor 1 (CXCR1) protein, a member of the G-protein-coupled receptor family. CXCR1 is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system.
Cat. No.: HY-121815
CAS No.: 956128-08-8
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TDI-2760 is an Aβ aggregation inhibitor with an IC50 of 1.67 μM. TDI-2760 can inhibit the Aβ-fibrinogen interaction and Aβ aggregation, and also modulate the contact system activation induced by Aβ42. TDI-2760 can be used in research related to vascular abnormalities and Aβ aggregation in Alzheimer's disease .
Cat. No.: HY-16785A
CAS No.: 755013-59-3
Synonyms: INXN-1001 racemate; RG-115932 racemate
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Veledimex racemate (INXN-1001 racemate) is the racemate of veledimex. Veledimex is an orally available, small-molecule activator ligand for the RheoSwitch Therapeutic System .
Cat. No.: HY-U00280
CAS No.: 908608-06-0
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Potassium Channel Activator 1 ((2,4-Dimethyl-6-morpholin-4-yl-pyridin-3-yl)-carbamic acid benzyl ester) is a potassium channel activator. Potassium Channel Activator 1 can be used for the study diseases or symptoms of dopaminergic system disorders .
Cat. No.: HY-113313S2
Purity: 99.30%
Cat. No.: HY-P5741
CAS No.: 877120-59-7
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Cat. No.: HY-W337680
CAS No.: 192883-12-8
N-3-Hydroxydecanoyl-L-homoserine lactone is a type of N-acyl-L-homoserine lactone (AHL), which is a class of signaling molecules in bacterial quorum sensing systems, and it has a weak activating effect on AbaR .
Cat. No.: HY-P1803
CAS No.: 120253-69-2
Synonyms: PKCε; PRKCE ; Peptide Epsilon
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Cat. No.: HY-W129230
CAS No.: 4419-92-5
Synonyms: 2-Hydroxybenzoic acid diethylamine
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Salicylic acid diethylamine (2-Hydroxybenzoic acid diethylamine) is a hormone involved in plant signaling. Salicylic acid diethylamine antagonizes the oxidative damaging effect of metal toxicity directly by acting as an antioxidant to scavenge the ROS and by activating the antioxidant systems of plants and indirectly by reducing uptake of metals from their medium of growth .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
