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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
349 Results for "
activation system
" in MedChemExpress (MCE) Product Catalog:
Products (349)
349 Results for "activation system" in MCE Product Catalog:
Cat. No.: HY-137721
CAS No.: 54447-85-7
Target:
Domaines de recherche:
Cyclic tri-AMP is a component of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), and acts as the second messenger in the immune response against viral infection. Cyclic tri-AMP binds to and activates DNA endonuclease NucC, results in cell death and exhibits antiviral activity .
Cat. No.: HY-P991113
CAS No.: 3002062-67-8
Synonyms: 609A
Target:
Domaines de recherche:
Cat. No.: HY-D2379
CAS No.: 1629965-68-9
Target:
Domaines de recherche:
HMRG is a fluorescent dye, which serves as the fluorescent active product generated by enzyme-activated fluorescent probes targeting proteases and glycosidases. Its detection mechanism relies on the intramolecular spirocyclization equilibrium: HMRG itself exists in an open non-spirocyclic structure under physiological pH, which maintains a conjugated π system and produces strong fluorescence; whereas its probe precursors (such as Leu-HMRG, Ac-GlyPro-HMRG and βGal-HMRG) exist in a closed spirocyclic form and show no fluorescence due to the disruption of the π-conjugated system; when the target enzyme cleaves the substrate fragment linked to the probe precursor, the closed spirocyclic structure converts to the open structure of HMRG, restoring the conjugated system and generating a strong fluorescent signal. Its detection wavelength is Ex/Em = 501/524 nm .
Cat. No.: HY-P2703
CAS No.: 81858-94-8
Target:
Domaines de recherche:
Category:
Quinones other families Anthraquinones Other Diseases Phenols Polyphenols Plants Disease Research Fields
Target:
Cat. No.: HY-169365
CAS No.: 2766689-18-1
Target:
Domaines de recherche:
2-Methylbiphenyl-oxadiazole-NH-Ph-CHO is a PD-L1 ligand. 2-Methylbiphenyl-oxadiazole-NH-Ph-CHO serves as the PD-L1 ligand of AUTAC PDL1 degrader-2 (HY-169363). 2-Methylbiphenyl-oxadiazole-NH-Ph-CHO activates the autophagy-lysosome system and upregulates autophagy-lysosome-related genes. 2-Methylbiphenyl-oxadiazole-NH-Ph-CHO is applicable for cancer research .
Cat. No.: HY-101654
CAS No.: 132579-32-9
Synonyms: BN 50730; LAU-8080
Domaines de recherche:
Rocepafant (BN 50730) is a specific platelet activating factor (PAF) antagonist. Rocepafant can be used in rheumatoid arthritis and nervous system research .
Cat. No.: HY-159916
CAS No.: 3031612-90-2
Target:
Domaines de recherche:
AYK004 is a TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. AYK004 is an adenine derivative with a favorable hydrophilic-lipophilic balance, which improves the loading capacity and stability in immunoadjuvant systems such as liposomes, while reducing the side effects of the immunoadjuvant system in systemic immunity .
Cat. No.: HY-136800
CAS No.: 78664-73-0
Target:
Domaines de recherche:
Posatirelin, a TRH analog, increases monoamine metabolites in the cerebral cortex, nucleus accumbens,
and striatum, and possibly exerts CNS activating effects through a modification of several neurotransmitter systems .
Cat. No.: HY-124382
CAS No.: 1345614-89-2
Target:
Domaines de recherche:
AS1928370 is a novel and central nervous system (CNS) penetrant TRPV1 antagonist and can prevent ligand-induced activation in vivo. AS1928370 is a promising agent for neuropathic pain research .
Cat. No.: HY-155371
CAS No.: 3032848-64-6
Domaines de recherche:
BT-PROTAC is a bioorthogonally activatable BRD4/BRD3 PROTAC degrader prodrug. BT-PROTAC is inactive when present alone, but upon activation by tetrazine compounds, it promotes the degradation of BRD4 and BRD3 via the ubiquitin-proteasome system, inhibits c-Myc expression, activates caspase-3, and induces apoptosis in breast cancer cells. BT-PROTAC can be used for breast cancer research .
Cat. No.: HY-107004
CAS No.: 161262-29-9
Synonyms: S-59 free base
Target:
Domaines de recherche:
Amotosalen (S-59 (free base)) is a light-activated, DNA and RNA-crosslinking psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD) .
Cat. No.: HY-15091
CAS No.: 170368-04-4
Synonyms: LF-150195
Target:
Domaines de recherche:
Anisperimus (LF-150195) is an immunosuppressant with the activity of enhancing activation-induced T cell death. Anisperimus enhances the sensitivity of T cells to anti-CD95 antibodies and other inducers by promoting the activation of caspase-8 and caspase-10 at the level of the death-inducing signaling complex (DISC). Anisperimus also promotes the development of Foxp3-expressing regulatory CD4 T cells, thereby preventing central nervous system autoimmunity .
Target:
Domaines de recherche:
Cardiovascular Disease Neurological Disease Metabolic Disease
Moxisylyte (Thymoxamine) is a selective α1A-adrenergic receptor antagonist. Moxisylyte competitively antagonizes the activation mediated by norepinephrine. Moxisylyte relaxes penile cavernous smooth muscle and aids erectile function. Moxisylyte is applicable to research related to erectile dysfunction and multiple system atrophy .
Cat. No.: HY-W019868
CAS No.: 77133-35-8
Category:
Target:
Cat. No.: HY-N7576
CAS No.: 221317-02-8
Category:
Liliaceae Anemarrhena asphodeloides Bunge Plants Disease Research Fields Inflammation/Immunology Steroids
Target:
Cat. No.: HY-P700753
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGA2; Alpha 2 Integrin; Prev. CD49B; Very Late activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen system 5; Platelet Membrane Glycoprotein Ia
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P703694
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA2; Alpha 2 Integrin; Prev. CD49B; Very Late activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen system 5; Platelet Membrane Glycoprotein Ia
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P705486
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA2; Alpha 2 Integrin; Prev. CD49B; Very Late activation Protein 2 Receptor, Alpha-2 Subunit; GPIa; Very Late activation Receptor Alpha-2 Subunit; CD49 Antigen-Like Family Member B; Human Platelet Alloantigen system 5; Platelet Membrane Glycoprotein Ia
Species:
Human
Source:
HEK293
Cat. No.: HY-125995
CAS No.: 2230581-03-8
Target:
Domaines de recherche:
NFE2L2 activator 3 (Compound 3) is a NFE2L2/NRF2 activator. NFE2L2 activator 3 specifically activates the NAD(P)H:quinone oxidoreductase (NQO1) enzyme, with its EC50 < 1 nM. NFE2L2 activator 3 can be used for research on respiratory system diseases such as chronic obstructive pulmonary disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
