Abazistobart
Based on 1 Customer Validation
Abazistobart is an immunostimulant and antineoplastic agent targeting the programmed cell death protein 1 (PDCD1). Abazistobart is a chimeric and humanized monoclonal antibody that specifically binds to PDCD1 to block the relevant signaling pathway, thereby activating the immune system and exerting antineoplastic activity. Abazistobart is promising for research of cancers.
For research use only. We do not sell to patients.
- Purity: 96.045%
- CAS No.: 3002062-67-8
- Molecular Weight:144.063 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG4 kappa
Human
PDCD1/PD-1/CD279
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG4-kappa
ELISA, FACS, Functional assay
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Immobilized PD-1 Protein, Human (147a.a, HEK293, His, HY-P70766) can bind Abazistobart. The EC50 for this effect is 126.9 ng/mL.
Chemical Information
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CAS No. 3002062-67-8
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Appearance Liquid
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Molecular Weight 144.063 kDa
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Color Colorless to light yellow
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SMILES
[Abazistobart]
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Synonyms
609A
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)