1. NF-κB Metabolic Enzyme/Protease
  2. Keap1-Nrf2 Quinone Reductase
  3. NFE2L2 activator 3

NFE2L2 activator 3 (Compound 3) is a NFE2L2/NRF2 activator. NFE2L2 activator 3 specifically activates the NAD(P)H:quinone oxidoreductase (NQO1) enzyme, with its EC50 < 1 nM. NFE2L2 activator 3 can be used for research on respiratory system diseases such as chronic obstructive pulmonary disease.

For research use only. We do not sell to patients.

NFE2L2 activator 3

NFE2L2 activator 3 Chemical Structure

CAS No. : 2230581-03-8

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Description

NFE2L2 activator 3 (Compound 3) is a NFE2L2/NRF2 activator. NFE2L2 activator 3 specifically activates the NAD(P)H:quinone oxidoreductase (NQO1) enzyme, with its EC50 < 1 nM. NFE2L2 activator 3 can be used for research on respiratory system diseases such as chronic obstructive pulmonary disease[1].

Molecular Weight

617.18

Formula

C29H33ClN4O5S2

CAS No.
SMILES

[C@@H]([C@](C(O)=O)(C)C)(C=1C(C)=C2C(=CC1)N(CC)N=N2)C3=CC(CN4S(=O)(=O)C=5C(O[C@H](CC)C4)=CC=CC5)=C(Cl)S3

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NFE2L2 activator 3
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HY-125995
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