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IPL344

IPL344 protects cells of various types from pro-apoptotic pressures and activates the Akt signaling system. IPL344 can be used for research of amyotrophic lateral sclerosis (ALS).

For research use only. We do not sell to patients.

CAS No.: 877120-59-7
Formula: C₄₁H₆₁N₇O₉
Molecular Weight:795.96

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

IPL344 Chemical Structure

CAS No.: 877120-59-7

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Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

IPL344 protects cells of various types from pro-apoptotic pressures and activates the Akt signaling system. IPL344 can be used for research of amyotrophic lateral sclerosis (ALS)^[1]^[2].

All Akt Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 877120-59-7
Molecular Weight 795.96
Formula C₄₁H₆₁N₇O₉
Sequence

Leu-Pro-Pro-Leu-Pro-Tyr-Pro
Sequence Shortening

LPPLPYP
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eran Ovadia, et al. Peptide compounds and methods of treating diseases using same. Patent. WO 2021/144798 Al

[2]. Meglio M. Akt Activator IPL344 Demonstrates Safety, Signs of Efficacy in Phase 1/2 Study of ALS[J]. Neurology Times, 2022: NA-NA.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References

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IPL344

High-Throughput Bioactive Compound Library

All Akt Isoforms