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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
153 Results for "
segmental
" in MedChemExpress (MCE) Product Catalog:
Products (153)
153 Results for "segmental" in MCE Product Catalog:
Cat. No.: HY-133813
CAS No.: 27773-65-5
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Apovincaminic acid is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid is used in the research of cerebrovascular diseases .
Cat. No.: HY-P991813
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Cat. No.: HY-118972
CAS No.: 1250849-11-6
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TPI-1917-49 is an agent that can cross the blood-brain barrier and reduce amyloid β (Aβ). TPI-1917-49 reduces the production of Aβ peptide segments by promoting the non-amyloidogenic pathway of amyloid precursor protein (APP) (increasing the generation of sAPPα mediated by α-secretase). TPI-1917-49 reduces amyloid plaques in mouse models. TPI-1917-49 can be used in Alzheimer's disease research .
Cat. No.: HY-165339
CAS No.: 54925-87-0
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Lysyl-phenylalanyl-lysine (Compound KFK) is a tripeptide and belongs to the peptide segments related to thrombospondin-1 (TSP-1) (HY-P0299). Lysyl-phenylalanyl-lysine can activate LAP-TGF-β1 and release active TGF-β1, thereby inhibiting abnormal expression of MMP. Lysyl-phenylalanyl-lysine can be used for research on skin aging-related diseases and poor wound healing .
Cat. No.: HY-183964
CAS No.: 3101670-39-4
DSPE-PEG2000-tetrazine is a synthetic phospholipid modified with PEG2000 and tetrazine moieties. DSPE-PEG2000-tetrazine gains improved steric stability via PEGylation. DSPE-PEG2000-tetrazine enables bioorthogonal click chemistry through its tetrazine segment, which selectively reacts with trans-cyclooctene (TCO) under complex biological environments. DSPE-PEG2000-tetrazine can be applied for researches related to click chemistry .
Cat. No.: HY-W673672
CAS No.: 4144-54-1
Synonyms: 4-Ketocapric acid; 4-ODA
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4-Oxodecanoic acid (4-Ketocapric acid) is a Sex pheromone component. 4-Oxodecanoic acid can be isolated from the sternal glands on the sixth abdominal segment of unmated female Vespa velutina. When mixed with 4-oxooctanoic acid at the natural secretion ratio of 0.78 in female wasps, 4-Oxodecanoic acid exhibits an attractive effect on male Vespa velutina. 4-Oxodecanoic acid can be used in population monitoring and control research on the invasive species Vespa velutina .
Cat. No.: HY-135470R
CAS No.: 13411-16-0
Synonyms: P-7138 (Standard)
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Nifurpirinol (P-7138) (Standard) is the analytical standard of Nifurpirinol (HY-135470). This product is intended for research and analytical applications. Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR). NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic β cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS) .
Synonyms: mPEG10000-Hydroxy; Polyethylene glycol monomethyl ether 10000
Cat. No.: HY-B0172AR
CAS No.: 2276-93-9
Synonyms: 3β-Hydroxy-5α-cholanic acid (Standard)
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Isoallolithocholic acid (Standard) is the analytical standard of Isoallolithocholic acid. This product is intended for research and analytical applications. Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation[1].
Cat. No.: HY-126179R
CAS No.: 20287-37-0
Synonyms: MG-13054 (Standard)
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Fenquizone (MG-13054) (Standard) is the analytical standard of Fenquizone (HY-126179). This product is intended for research and analytical applications. Fenquizone is an orally active diuretic. Fenquizone acts primarily on the diluting segment of the nephron cortex, similar to thiazide diuretics. Fenquizone demonstrates diuretic and natriuretic potency and duration of action comparable to thiazide diuretics but weaker than loop diuretics. Fenquizone reduces CH₂O without affecting TCH₂O, does not increase calcium/phosphate excretion, and has no loop or collecting duct effects. Fenquizone is used in the study of edema and hypertension.
Cat. No.: HY-188015
CAS No.: 3086791-85-4
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DBCO-PEG4-GGFG-Triptolide is a triptolide-based antibody-drug conjugate (ADC) payload, consisting of a DBCO click chemistry reactive group, a PEG4 linker, a cathepsin-cleavable GGFG peptide segment, and triptolide. DBCO-PEG4-GGFG-Triptolide binds to antibodies via glycosylation conjugation, releases active triptolide intracellularly to exert cytotoxic effects, and is commonly used in combination with camptothecin-class toxins (Exatecan (HY-13631) / DXd (HY-13631D)) for the preparation of dual-toxin ADCs .
Cat. No.: HY-P99315
CAS No.: 220651-94-5
Synonyms: BG 9588; Anti-Human CD40L Recombinant Antibody; Hu5c8
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Cat. No.: HY-W1123941A
Synonyms: Dopamine-PEG-Azide
Cat. No.: HY-119229
CAS No.: 815592-21-3
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VRT-325 is a CFTR modulator. VRT-325 inhibits disulfide cross-linking between cysteines in transmembrane segments 6 and 7 of CFTR and P-gp. VRT-325 promotes maturation of CFTR and P-gp processing mutants, rescues ΔF508-CFTR folding at the endoplasmic reticulum. VRT-325 binds ΔF508-CFTR nucleotide-binding domain 1, and increases mature ΔF508-CFTR cell surface expression and chloride conductance. VRT-325 can be used for the research of cystic fibrosis [1] [3].
Cat. No.: HY-P5519
CAS No.: 77568-41-3
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Cat. No.: HY-W1123941B
Synonyms: Dopamine-PEG1000-Azide
Cat. No.: HY-W1123941C
Synonyms: Dopamine-PEG2000-Azide
Cat. No.: HY-W1123941D
Synonyms: Dopamine-PEG3400-Azide
Cat. No.: HY-W1123941E
Synonyms: Dopamine-PEG5000-Azide
Cat. No.: HY-W1123941H
Synonyms: Dopamine-PEG10000-Azide
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
