14 Results for "

Fischeriana A

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Fischeriana A" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0732
CAS No.: 37905-08-1
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
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Cat. No.: HY-133209
CAS No.: 221456-63-9
Fischeria A is a norditerpene lactone of a new carbon skeleton, can be isolated from Euphorbia fischeriana .
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Cat. No.: HY-119767
CAS No.: 37905-07-0
Jolkinolide A is a diterpenoid, can be extracted from the roots of Euphorbia fischeriana Steud. Jolkinolide A exhibits anti-tumor activity, by affecting on angiogenesis of tumor tissues. Jolkinolide A significantly inhibits the Akt-STAT3-mTOR signaling pathway and reduces the expression of VEGF in A549 cells .
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Cat. No.: HY-N9280
CAS No.: 130466-20-5
ent-11α-Hydroxyabieta-8(14),13(15)-dien-16,12α-olide (compound 12) is a natural bioactive diterpenoid found in the roots of Euphorbia fischeriana .
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Cat. No.: HY-N12428
CAS No.: 65388-16-1
Synonyms: Caudicifolin; Fischeriana A
17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC50s of 631.9 ppm and 656.5 ppm, respectively.
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Cat. No.: HY-N10875
CAS No.: 768402-09-1
Euphebracteolatin B is a nature product that could be isolated from Euphorbia fischeriana .
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Cat. No.: HY-N10046
CAS No.: 960589-81-5
Synonyms: ent-Kaurane-3-oxo-17β-ol
ent-17-Hydroxykauran-3-one (ent-Kaurane-3-oxo-17β-ol; compound 7) is a kaurane-type diterpenoid that can be found in the roots of Euphorbia fischeriana .
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Cat. No.: HY-N0732R
CAS No.: 37905-08-1
Jolkinolide B (Standard) is the analytical standard of Jolkinolide B (HY-N0732). This product is intended for research and analytical applications. Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
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Cat. No.: HY-N2880
CAS No.: 125356-08-3
Antiquorin is a Diterpenoids product that can be isolated from the roots of Euphorbia fischeriana. .
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Cat. No.: HY-N19376
CAS No.: 247037-88-3
17-Hydroxyjolkinolide B is a diterpenoid found in Euphorbia fischeriana Steud. 17-Hydroxyjolkinolide B exhibits bioactivities .
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Cat. No.: HY-N1897
CAS No.: 133369-42-3
4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a Sesquiterpenoids product that can be isolated from the roots of Euphorbia fischeriana. .
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Cat. No.: HY-N21921
CAS No.: 81542-94-1
Synonyms: 2-epi-Euphornin I
Euphoscopin A (2-epi-Euphornin I) is a toxic lathyrane diterpene with Kv1.3 potassium channel inhibitory activity, can be found in fresh leaves and roots of Euphorbia helioscopia and aerial parts of Euphorbia fischeriana .
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Cat. No.: HY-N13201
CAS No.: 66583-59-3
12-Deoxyphorbol 13-palmitate is a traditional Chinese medicine monomer with antitumor activity that can be isolated from the root of Euphorbia fischeriana. 12-Deoxyphorbol 13-palmitate induces gastric cancer cell cycle arrest and apoptosis by regulating key cell cycle regulators such as cyclin Bcyclin A and CDC2. In addition, 12-Deoxyphorbol 13-palmitate can significantly weaken APOL2–SERCA2–PERK–HES1 signaling and slow liver fibrosis by targeting APOL2 .
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Cat. No.: HY-N11736
CAS No.: 37394-32-4
12-O-Tiglyl-phorbol 13-dodecanoate (TD13) is a potential inhibitor with anti-hepatic fibrosis activity, and it belongs to a series of derivatives of oral APOL2 inhibitors and anti-hepatic fibrosis agents. It shows no obvious toxicity in preclinical models. Compounds of the 12-O-Tiglyl-phorbol 13-dodecanoate series inhibit the expression of fibronectin, type I collagen and α-smooth muscle actin in hepatic stellate cells. 12-O-Tiglyl-phorbol 13-dodecanoate can be isolated from the Euphorbiaceae plant Euphorbia fischeriana, and it is applicable to the research of hepatic fibrosis .
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