37905-07-0
Chemical Structure
Jolkinolide A
- CAS No.: 37905-07-0
- Formula:C20H26O3
- Molecular Weight:314.42
IUPAC Name: (1aS,3aR,7aR,7bS,11bR)-4,4,7a,11-tetramethyl-3,3a,4,5,6,7,7a,7b-octahydro-2H-oxireno[2',3':1,10a]phenanthro[3,2-b]furan-10(11bH)-one
InChIKey: OYXDHOVYZKWSRM-PHJMNMFVSA-N
SMILES: CC1=C2[C@H]3O[C@]3([C@H]4C=C2OC1=O)CC[C@H]5[C@]4(CCCC5(C)C)C
Biological Activity: Jolkinolide A is a diterpenoid, can be extracted from the roots of Euphorbia fischeriana Steud. Jolkinolide A exhibits anti-tumor activity, by affecting on angiogenesis of tumor tissues. Jolkinolide A significantly inhibits the Akt-STAT3-mTOR signaling pathway and reduces the expression of VEGF in A549 cells[1].
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Jolkinolide A | 98.0% | Jolkinolide A is a diterpenoid, can be extracted from the roots of Euphorbia fischeriana Steud. Jolkinolide A exhibits anti-tumor activity, by affecting on angiogenesis of tumor tissues. Jolkinolide A significantly inhibits the Akt-STAT3-mTOR signaling pathway and reduces the expression of VEGF in A549 cells. | ||||||||||||||||||||
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Keywords
