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16:0-18:1 Tempo PC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Apoptosis (1) Autophagy (5) Biochemical Assay Reagents (4) Calcium Channel (1) DNA/RNA Synthesis (3) HIV (1) Isotope-Labeled Compounds (4) Mitochondrial Metabolism (4) NOD-like Receptor (NLR) (1) PINK1/Parkin (1) PROTAC Linkers (1) Reactive Oxygen Species (ROS) (7) Reference Standards (2) SOD (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (1) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (1)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Pyruvate Carboxylase (PC)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112879

Mito-TEMPO Maximum Cited Publications 164 Publications Verification	Calcium Channel PINK1/Parkin Mitochondrial Metabolism Apoptosis Autophagy NOD-like Receptor (NLR)	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
Mito-TEMPO is a mitochondria-targeted antioxidant. Mito-TEMPO induces mitophagy by activating the PINK1/Parkin pathway, inhibits NLRP3 inflammasome activation, restores mitochondrial membrane potential, and improves renal function and podocyte injury. Mito-TEMPO regulates Ca ²⁺ homeostasis, inhibits Bnip3 overexpression, shortens action potential duration, and exerts antiarrhythmic effects. Mito-TEMPO reverses premature senescence, reduces trabecular bone loss, and decreases cell apoptosis. Mito-TEMPO can be used in studies of chronic kidney disease, age-related cardiac dysfunction, postmenopausal osteoporosis, and ischemic stroke .

HY-100561

Tempol 25+ Cited Publications 4-Hydroxy-Tempo	Reactive Oxygen Species (ROS) Autophagy	Cancer
Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).

HY-W001187

*Tempo* 10+ Cited Publications	Mitochondrial Metabolism DNA/RNA Synthesis Reactive Oxygen Species (ROS)	Cancer
Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells .

HY-W002004

4-Amino-TEMPO 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl	Biochemical Assay Reagents	Inflammation/Immunology
4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-151847

N3-TEMPO 2 Publications Verification	ADC Linker	Others
N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-129242

Tempone 4-Oxo-Tempo	SOD	Others
Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .

HY-W001187S

Tempo-d18	DNA/RNA Synthesis Mitochondrial Metabolism Reactive Oxygen Species (ROS)	Cancer
Tempo-d₁₈ is the deuterium labeled Tempo . Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects .

HY-129242S

Tempone-15N,d16 4-Oxo-Tempo-¹⁵N,d₁₆	Isotope-Labeled Compounds	Others
Tempone- ¹⁵N,d₁₆ is the deuterium and ¹⁵N labeled Tempone .

HY-W001187R

Tempo (Standard)	Mitochondrial Metabolism DNA/RNA Synthesis Reactive Oxygen Species (ROS) Reference Standards	Cancer
Tempo (Standard) is the analytical standard of Tempo. This product is intended for research and analytical applications. Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells [4].

HY-100561S

Tempol-d17,15N 4-Hydroxy-Tempo-d₁₇,¹⁵N	Autophagy Reactive Oxygen Species (ROS)	Cancer
Tempol-d₁₇, ¹⁵N is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

HY-140512

Acid-PEG5-TEMPO	PROTAC Linkers	Cancer
Acid-PEG5-TEMPO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W002004S1

*4-Amino-TEMPO-d17* 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇	Isotope-Labeled Compounds Biochemical Assay Reagents	Inflammation/Immunology
4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-100561R

Tempol (Standard) 4-Hydroxy-Tempo (Standard)	Reference Standards Reactive Oxygen Species (ROS) Autophagy	Cancer
Tempol (Standard) is the analytical standard of Tempol. This product is intended for research and analytical applications. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).

HY-W777072

*4-Isocyanato-TEMPO,Technical grade*	HIV	Others
4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.

HY-W002004S

*4-Amino-TEMPO-d17,15N* 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇,¹⁵N	Isotope-Labeled Compounds Biochemical Assay Reagents	Inflammation/Immunology
4-Amino-TEMPO-d₁₇, ¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇, ¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-129242S1

Tempone-d16 4-Oxo-Tempo-d₁₆	Isotope-Labeled Compounds	Others
Tempone-d₁₆ is the deuterium labeled Tempone .

HY-100561S1

Tempol-d17 4-Hydroxy-Tempo-d₁₇	Autophagy Reactive Oxygen Species (ROS)	Cancer
Tempol-d₁₇ is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

HY-179762

*16:0 Tempo* PC**	Others	Others
16:0 Tempo PC is a phosphocholine with a TEMPO group. (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) is commonly used as a spin-label for lipid membrane studies. TEMPO alwayss acts as a spin probe are in electron resonance spectroscopy, as a paramagnetic contrast agent in NMR, and as oxygen-sensitive probes in biological systems.

HY-W705452

4-Palmitamido-TEMPO	Others	Metabolic Disease
4-Palmitamido-TEMPO is an aliphatic derivative of TEMPO. It is incorporated into vesicles and cell membranes and has been used to study the entrapment of molecules in phosphatidylcholine vesicles.

HY-179316

4-Phosphonooxy-tempo	Biochemical Assay Reagents	Others
4-Phosphonooxy-tempo is an anionic nitroxide spin probe. 4-Phosphonooxy-tempo can be transported by a band 3 protein to permeate the membrane and then react with reductants contained in cytosol. 4-Phosphonooxy-tempo can be used as biomembrane anion channel functional probe .

HY-179880

*16:0-18:1 Tempo* PC**	Others	Others
16:0-18:1 Tempo PC is a phosphocholine with a TEMPO group. (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) is commonly used as a spin-label for lipid membrane studies. TEMPO alwayss acts as a spin probe are in electron resonance spectroscopy, as a paramagnetic contrast agent in NMR, and as oxygen-sensitive probes in biological systems.

Cat. No.	Product Name

HY-L0122V

Asinex CNS Macrocycles Library	1,122 compounds
Several CNS multi-parameter scoring approaches have been reported: CNS-MPO, CNS-MPO V.2, CNS-TEMPO, which suggesting an algorithm to predict CNS-ike properties of new chemical entities. We have applied these scoring algorithms to select macrocycles satisfying multiple cut-offs and structural desirability criteria. The resulting set consists of 1,122 macrocyclic compounds with CNS-MPO > 4, CNS-MPO.v2 > 4, and CNS-TEMPO < 4 for CNS-related drug discovery and research.

Asinex CNS Macrocycles Library

1,122 compounds

Several CNS multi-parameter scoring approaches have been reported: CNS-MPO, CNS-MPO V.2, CNS-TEMPO, which suggesting an algorithm to predict CNS-ike properties of new chemical entities. We have applied these scoring algorithms to select macrocycles satisfying multiple cut-offs and structural desirability criteria. The resulting set consists of 1,122 macrocyclic compounds with CNS-MPO > 4, CNS-MPO.v2 > 4, and CNS-TEMPO < 4 for CNS-related drug discovery and research.

Cat. No.	Product Name	Type

HY-W002004

4-Amino-TEMPO 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl	Biochemical Assay Reagents
4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

4-Amino-TEMPO

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl

Biochemical Assay Reagents

4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

Cat. No.	Product Name	Chemical Structure

HY-W001187S

Tempo-d18
Tempo-d₁₈ is the deuterium labeled Tempo . Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects .

HY-129242S

Tempone-15N,d16
Tempone- ¹⁵N,d₁₆ is the deuterium and ¹⁵N labeled Tempone .

HY-100561S

Tempol-d17,15N
Tempol-d₁₇, ¹⁵N is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

HY-W002004S1

*4-Amino-TEMPO-d17*
4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

4-Amino-TEMPO-d17

4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-W002004S

*4-Amino-TEMPO-d17,15N*
4-Amino-TEMPO-d₁₇, ¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇, ¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

4-Amino-TEMPO-d17,15N

4-Amino-TEMPO-d₁₇, ¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇, ¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-129242S1

Tempone-d16
Tempone-d₁₆ is the deuterium labeled Tempone .

HY-100561S1

Tempol-d17
Tempol-d₁₇ is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .

Cat. No.	Product Name		Classification

HY-151847

N3-TEMPO 2 Publications Verification		Azide
N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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