1 Result for "

AACOCF3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AACOCF3" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-108611
CAS No.: 149301-79-1
Purity:  ≥99.0%
Synonyms: Arachidonyl trifluoromethyl ketone
Target:  

Phospholipase

Research Areas:  

Cardiovascular Disease

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease [3].
loading...
    loading...